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合肥物质科学研究院 [11]
长春光学精密机械与物... [4]
烟台海岸带研究所 [3]
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期刊论文 [20]
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2022 [21]
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Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin
期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:
Zhang, Lin
;
Li, Ling
;
Wang, Xia
;
Liu, Huimin
;
Zhang, Yibin
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浏览/下载:24/0
  |  
提交时间:2022/12/23
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
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  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Small molecule-assisted synthesis of carbon supported platinum intermetallic fuel cell catalysts
期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13
作者:
Song, Tian-Wei
;
Xu, Cong
;
Sheng, Zhu-Tao
;
Yan, Hui-Kun
;
Tong, Lei
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  |  
浏览/下载:33/0
  |  
提交时间:2022/12/23
The pathogenesis of organ fibrosis: Focus on necroptosis
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2022
作者:
Hao, Min
;
Han, Xin
;
Yao, Zhouhui
;
Zhang, Han
;
Zhao, Mengting
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  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
liver fibrosis
lung fibrosis
MLKL
necroptosis
RIPK1
3
tissue fibrosis
Period-timing bifurcation evolution in a nonlinear polarization rotation fiber laser
期刊论文
OPTIK, 2022, 卷号: 268
作者:
Ban, Xiaoqiang
;
Li, Xiaohui
;
Dong, Bo
;
Huang, Wobin
;
Zhong, Ming
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浏览/下载:21/0
  |  
提交时间:2022/10/25
Period -timing bifurcation
Passive fiber resonator
Soliton molecule
Small signal gain
Phase delay
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
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  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
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  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development
Engineering CpG-ASO-Pt-Loaded Macrophages (CAP@M) For Synergistic Chemo-/Gene-/Immuno-Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2022
作者:
Wang, Yuqi
;
Zhang, Lingpu
;
Liu, Yan
;
Tang, Linlin
;
He, Juan
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  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
cell therapy
DNA nanobiotechnology
drug delivery
macrophages
synergistic therapy
Fluorescent probes for biomolecule detection under environmental stress
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 431, 页码: 40
作者:
Han, Xiaoyue
;
Wang, Yue
;
Huang, Yan
;
Wang, Xiaoyan
;
Choo, Jaebum
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  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Fluorescent probe
Biomolecule
Environmental stress
Physiological
pathological processes
Chemical exposure
Structure-aware conditional variational auto-encoder for constrained molecule optimization
期刊论文
PATTERN RECOGNITION, 2022, 卷号: 126, 页码: 9
作者:
Yu, Junchi
;
Xu, Tingyang
;
Rong, Yu
;
Huang, Junzhou
;
He, Ran
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  |  
浏览/下载:18/0
  |  
提交时间:2022/06/06
Molecule optimization
Conditional generation
Drug discovery
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