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科研机构
上海药物研究所 [5]
兰州理工大学 [3]
合肥物质科学研究院 [3]
地理科学与资源研究所 [1]
数学与系统科学研究院 [1]
海洋研究所 [1]
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期刊论文 [14]
会议论文 [2]
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2021 [16]
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
Molecular and Clinical Characteristics of Primary Pulmonary Lymphoepithelioma-Like Carcinoma
期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8
作者:
Fan, Ying
;
Shan, Qianyun
;
Gong, Jiali
;
Qin, Jing
;
Lu, Hongyang
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/01/10
PPLELC
clinical characteristics
molecular characteristics
immunotherapy
PD-L1
TMB
Comparative transcriptome analysis reveals candidate genes for leaf color formation in a thermo-sensitive leaf-color mutant generated by carbon-ion beam in green wandering Jew (Tradescantia fluminensis)
期刊论文
SCIENTIA HORTICULTURAE, 2021, 卷号: 288, 页码: 17
作者:
Liu, Ruiyuan
;
Dong, Xicun
;
Zhang, Miaomiao
;
Qu, Ying
;
Jin, Wenjie
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/12/08
Green wandering Jew
Leaf-color mutant
Temperature
Transcriptome
Flavonoids
Photosynthesis
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer
期刊论文
BREAST CANCER, 2021
作者:
Zhu, Liang
;
Pan, Jia-Ni
;
Qian, Ziliang
;
Ye, Wei-Wu
;
Wang, Xiao-Jia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/06
CIN
TP53
BRCA1
LPWGS
Breast cancer
Identification of Common Driver Gene Modules and Associations between Cancers through Integrated Network Analysis
期刊论文
GLOBAL CHALLENGES, 2021, 页码: 13
作者:
Gao, Bo
;
Zhao, Yue
;
Gao, Yonghang
;
Li, Guojun
;
Wu, Ling-Yun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/10/26
driver gene module
gene mutation
mutual exclusivity
network analysis
signaling pathway
Characterization of Two Unique Cold-Active Lipases Derived from a Novel Deep-Sea Cold Seep Bacterium
期刊论文
MICROORGANISMS, 2021, 卷号: 9, 期号: 4, 页码: 16
作者:
Guo, Chenchen
;
Zheng, Rikuan
;
Cai, Ruining
;
Sun, Chaomin
;
Wu, Shimei
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/06/04
lipase
cold seep
cold-active
deep sea
overexpression
An improved particle swarm optimization algorithm and its application in solving forward kinematics of a 3-DoF parallel manipulator
期刊论文
Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, 2021, 卷号: 235, 期号: 5, 页码: 896-907
作者:
Zhang, Shuzhen
;
Yuan, Xiaolong
;
Docherty, Paul D
;
Yang, Kai
;
Li, Chunling
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/06/03
Benchmarking
Degrees of freedom (mechanics)
Inverse kinematics
Manipulators
Parameter estimation
Particle swarm optimization (PSO)
Reactive power
Stochastic systems
Complex optimization problems
Fast convergence speed
Improved particle swarm optimization algorithms
Mechanism simulation
Optimization problems
Parallel manipulators
Particle swarm optimization method
Three degree of freedoms
Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm
期刊论文
PHOTONICS RESEARCH, 2021, 卷号: 9, 期号: 2, 页码: 202-212
作者:
Li, Huanhao
;
Woo, Chi Man
;
Zhong, Tianting
;
Yu, Zhipeng
;
Luo, Yunqi
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/04/06
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