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科研机构
上海药物研究所 [24]
合肥物质科学研究院 [14]
南京地理与湖泊研究所 [6]
海洋研究所 [5]
烟台海岸带研究所 [2]
沈阳自动化研究所 [1]
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期刊论文 [54]
发表日期
2021 [54]
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An overview of kinase downregulators and recent advances in discovery approaches
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:
Wang, Beilei
;
Wu, Hong
;
Hu, Chen
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/25
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
Apatinib vs Placebo in Patients With Locally Advanced or Metastatic, Radioactive Iodine-Refractory Differentiated Thyroid Cancer The REALITY Randomized Clinical Trial
期刊论文
JAMA ONCOLOGY, 2021
作者:
Lin, Yansong
;
Qin, Shukui
;
Li, Zhiyong
;
Yang, Hui
;
Fu, Wei
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/25
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
Feasibility of source identification by DOM fingerprinting in marine pollution events
期刊论文
MARINE POLLUTION BULLETIN, 2021, 卷号: 173, 页码: 9
作者:
Jiang, Ming
;
Sheng, Yanqing
;
Tian, Chongguo
;
Li, Changyu
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  |  
浏览/下载:12/0
  |  
提交时间:2022/06/16
Dissolved organic matter
Excitation-emission matrix spectrum
Parallel factor analysis
Marine pollution events
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
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  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
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  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Metabolomic analysis of coelomic fluids reveals the physiological mechanisms underlying evisceration behavior in the sea cucumber Apostichopus japonicus
期刊论文
AQUACULTURE, 2021, 卷号: 543, 页码: 9
作者:
Ding, Kui
;
Zhang, Libin
;
Huo, Da
;
Guo, Xueying
;
Liu, Xiang
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  |  
浏览/下载:43/0
  |  
提交时间:2021/12/07
Echinoderm
Sea cucumber
Evisceration
Metabolite
Metabolic pathway
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
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  |  
浏览/下载:33/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
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