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科研机构
上海药物研究所 [5]
合肥物质科学研究院 [4]
近代物理研究所 [2]
自动化研究所 [1]
内容类型
期刊论文 [12]
发表日期
2021 [12]
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Immune checkpoint inhibitor-related adverse events in lung cancer: Real-world incidence and management practices of 1905 patients in China
期刊论文
THORACIC CANCER, 2021
作者:
Shi, Yuequan
;
Fang, Jian
;
Zhou, Chengzhi
;
Liu, Anwen
;
Wang, Yan
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2022/01/25
advanced lung cancer
immune checkpoint inhibitors
immune-related adverse events
real-world data
The prognostic impact of mild and severe immune-related adverse events in non-small cell lung cancer treated with immune checkpoint inhibitors: a multicenter retrospective study
期刊论文
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2021
作者:
Wang, Wenxian
;
Gu, Xiaodong
;
Wang, Liping
;
Pu, Xingxiang
;
Feng, Huijing
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/01/10
Non-small cell lung cancer
PD-L1
Immune checkpoint inhibitor
Immune-related adverse event
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition
期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:
Gao, Jing
;
Zhang, Hanwu
;
Zhou, Fengqi
;
Hou, Bo
;
Chen, Meiwan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Cancer immunotherapy
siRNA delivery
Acid-activatible micelleplex
CDK4
6 inhibitor
PD-L1 knockdown
Direct Approach to 3-Fluoroindoles and 3,3-Difluoroindolines from 2,2-Difluoro-2-phenylethan-1-amines via C-H/N-H Coupling
期刊论文
SYNTHESIS-STUTTGART, 2021, 页码: 12
作者:
Zhang, Lanfei
;
Zhang, Xiaofei
;
Cui, Yongmei
;
Yang, Chunhao
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
picolinamide
3,3-difluoroindolines
3-fluoroindoles
directing groups
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:
Liu, Chenglong
;
Zhou, Feilong
;
Yan, Ziqin
;
Shen, Lian
;
Zhang, Xichen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/06/11
immunotherapy
PD-1/PD-L1
TGF-beta
tumour immune microenvironment
Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy
期刊论文
NEOPLASIA, 2021, 卷号: 23, 期号: 3, 页码: 281-293
作者:
Wang, Fengling
;
Ye, Wenling
;
Wang, Shuang
;
He, Yongxing
;
Zhong, Haiyang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/12/10
PD-1
PD-L1
Inhibitor
APBC
Cancer immunotherapy
Case Report: Significant Response to Immune Checkpoint Inhibitor Camrelizumab in a Heavily Pretreated Advanced ER+/HER2-Breast Cancer Patient With High Tumor Mutational Burden
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10
作者:
Wang, Rong
;
Yang, Yuchen
;
Ye, Wei-Wu
;
Xiang, Jianxing
;
Chen, Songan
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/04/26
breast cancer
immunotherapy
biomarker
TMB
NGS
molecular monitoring
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
Safety and efficacy of combination therapy using programmed cell death protein-1/programmed cell death ligand-1 inhibitors and radiotherapy in patients with non-small-cell lung cancer: A systematic review and meta-analysis
期刊论文
CANCER MEDICINE, 2021, 页码: 19
作者:
Geng, Yichao
;
Zhang, Qiuning
;
Feng, Shuangwu
;
Li, Chengcheng
;
Wang, Lina
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/10
combined radio-immunotherapy
meta-analysis
non-small-cell lung cancer
programmed cell death protein-1/programmed cell death ligand-1 inhibitors
radiotherapy
systematic review
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