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浏览/检索结果: 共4条，第1-4条 帮助 限定条件 发表日期：2021     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17 作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He;  Liu, Shan-Kui 收藏  |  浏览/下载：69/0  |  提交时间：2021/11/04 Tetrahydrobenzo[b]thiophen-2-yl)urea  alpha-Glucosidase inhibitors  Non-competitive inhibitor  Molecular docking  Anti-hyperglycaemic activity  Type 2 diabetes   A glimpse of deep-sea adaptation in chemosynthetic holobionts: Depressurization causes DNA fragmentation and cell death of methanotrophic endosymbionts rather than their deep-sea Bathymodiolinae host 期刊论文 MOLECULAR ECOLOGY, 2021, 卷号: 30, 期号: 10, 页码: 2298-2312 作者:  Chen, Hao;  Wang, Minxiao;  Li, Mengna;  Lian, Chao;  Zhou, Li 收藏  |  浏览/下载：72/0  |  提交时间：2021/06/04 bathymodiolinae mussel  chemosynthetic symbiosis  deep‐  sea adaptation  hydrostatic pressure  methane‐  oxidizing bacteria   Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855 作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504 作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian 收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24 Medulloblastoma  Hedgehog signaling  pathway  Drug resistance  GLI  BRD4