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浏览/检索结果: 共69条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文 ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22 作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/18 Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10 作者:  Zou, Hui-xi;  Zhang, Yu-feng;  Zhong, Da-fang;  Jiang, Yong;  Liu, Fei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/04 furmonertinib  autoinduction  food effect  alkaline phosphatase  body weight  pharmacokinetics  modeling and simulation  NSCLC   Discrete genetic loci in human gutBacteroides thetaiotaomicron confer pectin metabolism 期刊论文 CARBOHYDRATE POLYMERS, 2021, 卷号: 272, 页码: 13 作者:  Li, Meixia;  Li, Saijuan;  Guo, Xiaozhen;  Guo, Ciliang;  Wang, Yeqin 收藏  |  浏览/下载：62/0  |  提交时间：2021/11/04 Polysaccharide  Pectin  Human gut microbiota  Metabolism  Bacteroides   Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14 作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia 收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04 Type 2 diabetes mellitus  Dual FABP4/5 inhibitors  Anti-lipolytic and anti-inflammatory effects  Metabolic stability  Anti-diabetic activities   Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9 作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu 收藏  |  浏览/下载：40/0  |  提交时间：2022/01/04 phosphoinositide 3-kinase (PI3K)  activation  inhibition  activity-dependent conformational changes   Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11 作者:  Guo, Yuejiao;  Liu, Fang;  Chen, MingCang;  Tian, Qiang;  Tian, Xiaoting 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/16 chronic kidney disease  Huangjinsan  metabolomics  renoprotection  traditional Chinese medicine   Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy 期刊论文 Chinese Medicine, 2021, 卷号: 16, 期号: 1 作者:  Wu,Gaosong;  Zhao,Jing;  Zhao,Jing;  Song,Nixue;  Zheng,Ningning 收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01 Coronary heart disease  Syndrome differentiation  Traditional Chinese Medicine  Proteomics  Metabolomics  Network pharmacology   Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269 作者:  Yin, Jianpeng;  Zhan, Desheng;  Ma, Hui;  Liu, Huanan;  Yu, Lifang 收藏  |  浏览/下载：36/0  |  提交时间：2021/12/16 YLF466D  AMPK activator  glucose metabolism  lipid metabolism  MIRI  domino reaction  C-H activation   DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing 期刊论文 CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 2004-+ 作者:  Li, Yufeng;  Xu, Junyu;  Lu, Yuting;  Bian, Hua;  Yang, Lin 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/18 Introducing the authors 期刊论文 CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 1896-1900 作者:  Li, Jingya;  Jiang, Hui;  Li, Hongliang;  Jiang, Changtao;  Liu, Junli 收藏  |  浏览/下载：16/0  |  提交时间：2022/01/18