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浏览/检索结果: 共27条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14 作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 Type 2 diabetes mellitus  Dual FABP4/5 inhibitors  Anti-lipolytic and anti-inflammatory effects  Metabolic stability  Anti-diabetic activities   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04 Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16 The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway 期刊论文 FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15 作者:  Fu, Yadong;  Xiao, Zhun;  Tian, Xiaoting;  Liu, Wei;  Xu, Zhou 收藏  |  浏览/下载：30/0  |  提交时间：2022/01/04 traditional Chinese medicine  JY5 formula  fuzheng huayu  hepatic fibrosis  notch signaling pathway   Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge 期刊论文 PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19 作者:  Xiong, Zhaoping;  Jeon, Minji;  Allaway, Robert J.;  Kang, Jaewoo;  Park, Donghyeon 收藏  |  浏览/下载：22/0  |  提交时间：2021/11/04 Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088 作者:  Lu, Tian;  Lu, Haibo;  Duan, Zhe;  Wang, Jun;  Han, Jie 收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04 Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18 作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng 收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17 Axl  Cancer  Inhibitor  Pyrrolo[2,3-d]pyrimidine   Structural basis for genome packaging, retention, and ejection in human cytomegalovirus 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 14 作者:  Li, Zhihai;  Pang, Jingjing;  Dong, Lili;  Yu, Xuekui 收藏  |  浏览/下载：15/0  |  提交时间：2021/11/04 Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237 作者:  Liang, Xuewu;  Sun, Chenxia;  Li, Chunpu;  Yu, Haolan;  Wei, Xiaohui 收藏  |  浏览/下载：20/0  |  提交时间：2021/08/17 NaNbO3-(Bi0.5Li0.5)TiO3 Lead-Free Relaxor Ferroelectric Capacitors with Superior Energy-Storage Performances via Multiple Synergistic Design 期刊论文 ADVANCED ENERGY MATERIALS, 2021, 页码: 12 作者:  Xie, Aiwen;  Zuo, Ruzhong;  Qiao, Zhenliang;  Fu, Zhengqian;  Hu, Tengfei 收藏  |  浏览/下载：65/0  |  提交时间：2021/08/17 energy-storage capacitors  lead-free relaxor ferroelectrics  multiscale structure evolution  nanodomains