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浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Chen, Cheng;  Ren, Yong-mei;  Zhu, Jian-zhong;  Chen, Jia-li;  Feng, Zhe-ling 收藏  |  浏览/下载：56/0  |  提交时间：2022/01/04 Ainsliadimer C  interleukin-1 beta  macrophages  NLRP3 inflammasome  Sirtuin 1  adipose tissue inflammation  obesity  metabolic disorders  EX-527  dexamethasone   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu 收藏  |  浏览/下载：41/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文 NATURE, 2021, 页码: 24 作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan 收藏  |  浏览/下载：53/0  |  提交时间：2021/11/04 Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation 期刊论文 ADVANCED THEORY AND SIMULATIONS, 2021, 页码: 13 作者:  Li, Yao;  Wang, Tong;  Zhang, Juanrong;  Shao, Bin;  Gong, Haipeng 收藏  |  浏览/下载：50/0  |  提交时间：2021/11/04 "wedge" effect  molecular dynamics simulations  N-terminal domain  SARS-CoV-2  Spike protein   ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 9 作者:  Chen, Yuning;  Zhang, Ya-Nan;  Yan, Renhong;  Wang, Guifeng;  Zhang, Yuanyuan 收藏  |  浏览/下载：67/0  |  提交时间：2021/11/04 Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228 作者:  Zheng, Mengmeng;  Li, Chunpu;  Zhou, Mi;  Jia, Ru;  Cai, Gang 收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04 Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya 收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   Molecular simulation studies of the interactions between the human/ pangolin/cat/bat ACE2 and the receptor binding domain of the SARS-CoV-2 spike protein 期刊论文 BIOCHIMIE, 2021, 卷号: 187, 页码: 1-13 作者:  Ma, Shaojie;  Li, Hui;  Yang, Jun;  Yu, Kunqian 收藏  |  浏览/下载：68/0  |  提交时间：2021/08/17 SARS-CoV-2  ACE2  Molecular simulation  Binding energy  Animal hosts