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科研机构
上海药物研究所 [3]
自动化研究所 [3]
数学与系统科学研究院 [1]
重庆绿色智能技术研究... [1]
内容类型
期刊论文 [8]
发表日期
2020 [8]
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发表日期:2020
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Construction of a novel bispecific fusion protein to enhance targeting for pancreatic cancer imaging
期刊论文
BIOMATERIALS, 2020, 期号: 255, 页码: 120161
作者:
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/09/07
Bispecific targeting
Fusion protein
Antibody
Molecular imaging
Pancreatic cancer
Nanopore Detection of Metal Ions: Current Status and Future Directions
期刊论文
SMALL METHODS, 2020, 页码: 20
作者:
Roozbahani, Golbarg Mohammadi
;
Chen, Xiaohan
;
Zhang, Youwen
;
Wang, Liang
;
Guan, Xiyun
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  |  
浏览/下载:70/0
  |  
提交时间:2020/10/12
biomolecules
chemical reactions
metal ion
molecular translocation
nanopore
Development of a Novel Histone Deacetylase-Targeted Near-Infrared Probe for Hepatocellular Carcinoma Imaging and Fluorescence Image-Guided Surgery
期刊论文
MOLECULAR IMAGING AND BIOLOGY, 2020, 卷号: 22, 期号: 3, 页码: 476-485
作者:
Tang, Chu
;
Du, Yang
;
Liang, Qian
;
Cheng, Zhen
;
Tian, Jie
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/06/22
Specific targeting probe
Histone deacetylase
Fluorescence imaging
Hepatocellular carcinoma
Fluorescence image-guided surgery
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:
Hou, Zeng
;
Min, Wenjian
;
Zhang, Rukang
;
Niu, Ao
;
Li, Yuanqing
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Histone methylation
SET7
Small-molecule inhibitor
Virtual screening
Molecular probe
Probe Efficient Feature Representation of Gapped K-mer Frequency Vectors from Sequences Using Deep Neural Networks
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 657-667
作者:
Cao, Zhen
;
Zhang, Shihua
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/05/24
DNA
Bioinformatics
Kernel
Feature extraction
Support vector machines
Genomics
Task analysis
Bioinformatics
machine learning
gapped k-mer
deep neural network
transcription factor binding site prediction
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
K-nearest Neighbor Based Locally Connected Network for Fast Morphological Reconstruction in Fluorescence Molecular Tomography
期刊论文
IEEE Transactions on Medical Imaging, 2020, 卷号: 无, 期号: 无, 页码: 无
作者:
Meng, Hui
;
Gao, Yuan
;
Yang, Xin
;
Wang, Kun
;
Tian, Jie
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  |  
浏览/下载:7/0
  |  
提交时间:2020/04/29
Fluorescence Tomography
Machine Learning
Brain
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
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