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科研机构
上海药物研究所 [5]
合肥物质科学研究院 [2]
上海应用物理研究所 [1]
内容类型
期刊论文 [8]
发表日期
2020 [8]
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发表日期:2020
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A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188
作者:
Liang, Xiaofei
;
Jiang, Zongru
;
Huang, Zhenghui
;
Li, Feng
;
Chen, Cheng
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  |  
浏览/下载:27/0
  |  
提交时间:2020/11/26
PI4K kinase
Kinase inhibitor
Malaria
Blood stage
Liver stage
Discovery of synergistic activity of fluoroquinolones in combination with antimicrobial peptides against clinical polymyxin-resistant Pseudomonas aeruginosa DK2
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 2, 页码: 413-417
作者:
Zheng, Xinyu
;
Cao, Qiao
;
Cao, Qin
;
Mao, Fei
;
Li, Xiaokang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Polymyxin B
Pseudomonas aeruginosa
Fluoroquinolones
Synergy
Cystic fibrosis
Antimicrobial peptides
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation
期刊论文
ONCOGENE, 2020, 卷号: 39
作者:
Jin, Ying
;
Bao, Hua
;
Le, Xiuning
;
Fan, Xiaojun
;
Tang, Ming
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  |  
浏览/下载:26/0
  |  
提交时间:2020/11/26
Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Xie, Zhu-qing
;
Tian, Xiao-ting
;
Zheng, Yue-ming
;
Zhan, Li
;
Chen, Xue-qin
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  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
geissoschizine methyl ether
Uncaria rhynchophyll
antiepileptic drug
hippocampal neurons
action potential
nicotinic acetylcholine receptors
voltage-gated ion channels
mouse seizure model
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
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  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage
期刊论文
PLOS PATHOGENS, 2020, 卷号: 16, 期号: 3, 页码: -
作者:
Zhou, B
;
Zhen, XK
;
Zhou, H
;
Zhao, FY
;
Fan, CP
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/09/06
CRYSTAL-STRUCTURE
BACTERIOPHAGE ENDOLYSINS
STAPHYLOCOCCUS-AUREUS
DIABETIC FOOT
LYSIN
RECOGNITION
MECHANISM
PROTEIN
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