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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2020     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802 作者:  Lv, Kaikai;  Chen, Weicong;  Chen, Danqi;  Mou, Jie;  Zhang, Huijie 收藏  |  浏览/下载：12/0  |  提交时间：2020/12/21 Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction 期刊论文 INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713 作者:  Damaneh, Mohammadali Soleimani;  Hu, Jian-Ping;  Huan, Xia-Juan;  Song, Shan-Shan;  Tian, Chang-Qing 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 BET inhibitor  Cell proliferation  Apoptosis  Anti-cancer agent   BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis 期刊论文 THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12 作者:  Li, Guang;  Zheng, Yan-Hua;  Xu, Li;  Feng, Juan;  Tang, Hai-Long 收藏  |  浏览/下载：47/0  |  提交时间：2020/12/24 apoptosis  BRD4 inhibitor  G1 phase cell cycle checkpoint  multiple myeloma   Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 3956-3975 作者:  Li, Zizhou;  Xiao, Senhao;  Yang, Yaxi;  Chen, Chao;  Lu, Tian 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Uncommon nornardosinane, seconeolemnane and related sesquiterpenoids from Xisha soft coral Litophyton nigrum 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 96, 页码: 8 作者:  Yang, Fan;  Li, Song-Wei;  Zhang, Jun;  Liang, Lin-Fu;  Lu, Yan-Hua 收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 Litophyton nigrum  Nornardosinane  Seconeolemnane  Cytotoxicity  Inhibitory activity   A patent review of BRD4 inhibitors (2013-2019) 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2020, 卷号: 30, 期号: 1, 页码: 57-81 作者:  Lu, Tian;  Lu, Wenchao;  Luo, Cheng 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Bromodomain-containing protein 4 (BRD4)  bromodomain and extra-terminal (BET) family  small molecule inhibitors  cancer  patent  therapeutic potential