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浏览/检索结果: 共94条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186 作者:  Zheng, Wei;  Wang, Zhen;  Jiang, Xiangrui;  Zhao, Qingjie;  Shen, Jingshan 收藏  |  浏览/下载：25/0  |  提交时间：2021/05/24 Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52 期刊论文 ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284 作者:  Ma, Mengna;  Guo, Shimeng;  Lin, Xi;  Li, Shanshan;  Wu, Yiran 收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24 1-Phenyl-N-(benzothiazol-2-yl)methanimine derivatives as Middle East respiratory syndrome coronavirus inhibitors 期刊论文 RSC ADVANCES, 2020, 卷号: 10, 期号: 71, 页码: 43299-43311 作者:  Hu, Min-Qi;  Li, Heng;  Lin, Ying;  Zhang, Ying;  Tang, Jie 收藏  |  浏览/下载：51/0  |  提交时间：2021/05/24 A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor 期刊论文 CELL RESEARCH, 2020, 页码: 11 作者:  Sun, Wen;  Chen, Li-Nan;  Zhou, Qingtong;  Zhao, Li-Hua;  Yang, Dehua 收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24 Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772 作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou;  Sun, Dan-dan;  Shu, Zhihao 收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 Transcriptional and proteomic insights into the host response in fatal COVID-19 cases 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 45, 页码: 28336-28343 作者:  Wu, Meng;  Chen, Yaobing;  Xia, Han;  Wang, Changli;  Tan, Chin Yee 收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24 COVID-19  SARS-CoV-2  neutrophil  fibrosis  NETosis   Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Zhu, Lin;  Zhang, Chun-yuan;  Li, Dong-ping;  Chen, Hu-biao;  Ma, Jiang 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 herb-induced liver injury  hepatic sinusoidal obstruction syndrome  pyrrolizidine alkaloids  Tu-San-Qi  Gynura japonica   Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387 作者:  Li, Zhe;  Li, Xin;  Huang, Yi-You;  Wu, Yaoxing;  Liu, Runduo 收藏  |  浏览/下载：74/0  |  提交时间：2020/12/24 virtual screening  SARS-CoV-2  drug repurposing  free energy perturbation  main protease   SARS-CoV-2 and Three Related Coronaviruses Utilize Multipke ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig 期刊论文 JOURNAL OF VIROLOGY, 2020, 卷号: 94, 期号: 22, 页码: 14 作者:  Li, Yujun;  Wang, Haimin;  Tang, Xiaojuan;  Fang, Shisong;  Ma, Danting 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/21 ACE2  ACE2-Ig  SARS-CoV-2  entry inhibitor  host range   DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation 期刊论文 BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69 作者:  Lv, Jianlu;  Wang, Wei;  Zhu, Xialin;  Xu, Xiaoju;  Yan, Qiuying 收藏  |  浏览/下载：28/0  |  提交时间：2020/12/21 Alzheimer'sdisease  Microglia  AMPK alpha 1  DW14006  Phagocytosis  Neuro-inflammation