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DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models 期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:  Zhang, Zongwang;  Wu, Yanwei;  Wu, Bing;  Qi, Qing;  Li, Heng
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao
收藏  |  浏览/下载:25/0  |  提交时间:2020/03/20
Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:  Chen, Deheng;  Lu, Tian;  Yan, Ziqin;  Lu, Wenchao;  Lyu, Xilin
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01
Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity 期刊论文
ONCOIMMUNOLOGY, 2019, 卷号: 8, 期号: 11, 页码: 9
作者:  Zhou, Heng;  Perez-Lanzon, Maria;  Humeau, Juliette;  Wang, Yan;  Senovilla, Laura
收藏  |  浏览/下载:79/0  |  提交时间:2019/11/10
Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1386-1393
作者:  Cui, Xue;  Guo, Yu-e;  Fang, Jia-hui;  Shi, Chang-jie;  Suo, Na
收藏  |  浏览/下载:70/0  |  提交时间:2020/07/01
Evaluation of Kinetic Inhibition of Methane Hydrate Formation by a Copolymer of N-Vinylcaprolactam with 1-Vinylimidazole 期刊论文
ENERGY & FUELS, 2019, 卷号: 33, 期号: 10, 页码: 10133-10142
作者:  Long, Zhen;  Lu, Zhilin;  Ding, Qihang;  Zhou, Xuebing;  Lei, Jiao
收藏  |  浏览/下载:24/0  |  提交时间:2020/10/29
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:  Wang, Jubo;  Li, Tinghan;  Zhao, Tengteng;  Wu, Tizhi;  Liu, Chuang
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
Inhibition of the BET family reduces its new target gene IDO1 expression and the production of L-kynurenine 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 13
作者:  Tian, Chang-Qing;  Chen, Lin;  Chen, Hua-Dong;  Huan, Xia-Juan;  Hu, Jian-Ping
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/01


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