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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2019     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models 期刊论文 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1, 页码: 16 作者:  Peng, Xia;  Hou, Pengcong;  Chen, Yi;  Dai, Yang;  Ji, Yinchun 收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01 Kinase inhibitor  FGFR  CSF-1R  Tumor microenvironment   Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488 作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer 期刊论文 NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15 作者:  Jin, Nan;  Bi, Aiwei;  Lan, Xiaojing;  Xu, Jun;  Wang, Xiaomin 收藏  |  浏览/下载：61/0  |  提交时间：2020/07/01 Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study 期刊论文 ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368 作者:  Wei, Peng;  Liu, Bo;  Wang, Ruifeng;  Gao, Yinglei;  Li, Lanlan 收藏  |  浏览/下载：103/0  |  提交时间：2020/07/01 Fibroblast growth factor  Tyrosine kinase receptor  Structure-based  Crystallography  Selectivity  Hybrid  5-Hydrosulfonyl-5H- pyrrolo[2.3-b]pyrazine  Inhibitor   discoveryofaseriesofdimethoxybenzenefgfrinhibitorswith5hpyrrolo23bpyrazinescaffoldstructureactivityrelationshipcrystalstructuralcharacterizationandinvivostudy 期刊论文 actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 2, 页码: 351 作者:  Wei Peng;  Liu Bo;  Wang Ruifeng;  Gao Yinglei;  Li Lanlan 收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Fibroblast growth factor  Tyrosine kinase receptor  Structure-based  Crystallography  Selectivity  Hybrid  5-Hydrosulfonyl-5Hpyrrolo 2  3-bpyrazine  Inhibitor   c11anovelfibroblastgrowthfactorreceptor1fgfr1inhibitorsuppressesbreastcancermetastasisandangiogenesis 期刊论文 actapharmacologicasinica, 2019, 卷号: 40, 期号: 6, 页码: 823 作者:  Chen Zhuo;  Tong Linjiang;  Tang Baiyou;  Liu Hongyan;  Wang Xin 收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01 SELECTIVE INHIBITOR  THERAPEUTIC TARGET  DISCOVERY  ACTIVATION  EXPRESSION  PATHWAY  POTENT  C11  FGFR1 inhibitor  antitumor  breast cancer  metastasis  angiogenesis   Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1 期刊论文 Journal of Experimental & Clinical Cancer Research, 2019, 卷号: 38, 期号: 1 作者:  Xia Peng;  Pengcong Hou;  Yi Chen;  Yang Dai;  Yinchun Ji 收藏  |  浏览/下载：1/0  |  提交时间：2021/12/01