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生态环境研究中心 [4]
昆明植物研究所 [2]
上海药物研究所 [1]
大连化学物理研究所 [1]
武汉物理与数学研究所 [1]
内容类型
期刊论文 [9]
发表日期
2019 [9]
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The molecular mechanism of the antagonistic activity of hydroxylated polybrominated biphenyl (OH-BB80) toward thyroid receptor beta
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 697, 页码: -
作者:
Zhang, Xiaofang
;
Cui, Shixuan
;
Pan, Liumeng
;
Dong, Wenhua
;
Ma, Mei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Hydroxylated brominated biphenyls
Endocrine disrupting effect
Molecular interactions
Metabolic activation
Estrogen-related receptor gamma is a novel target for Lower-Chlorinated Polychlorinated Biphenyls and their hydroxylated and sulfated metabolites
期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 254, 页码: -
作者:
Cao, Lin-Ying
;
Ren, Xiao-Min
;
Guo, Liang-Hong
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  |  
浏览/下载:14/0
  |  
提交时间:2020/09/10
Lower-chlorinated PCBs (LC-PCBs)
OH-PCBs
PCB sulfates
Estrogen-related receptor gamma (ERR gamma)
Endocrine disruption effect
Binding and activity of sulfated metabolites of lower-chlorinated polychlorinated biphenyls towards thyroid hormone receptor alpha
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 180, 页码: 686-692
作者:
Ren, Xiao-Min
;
Li, Chuan-Hai
;
Zhang, Jian-Qing
;
Guo, Liang-Hong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/09/10
Lower-chlorinated polychlorinated biphenyls
LC-PCB sulfates
TR
Agonistic activity
TH system disruption effect
Isolation and bioactive evaluation of flavonoid glycosides from Lobelia chinensis Lour using two-dimensional liquid chromatography combined with label-free cell phenotypic assays
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1601, 页码: 224-231
作者:
Wang, Jixia
;
Chen, Linlin
;
Qu, Lala
;
Li, Kuiyong
;
Zhao, Yaopeng
收藏
  |  
浏览/下载:274/0
  |  
提交时间:2019/12/02
Flavonoid glycosides
Separation and purification
G protein-coupled receptor 35
Two-dimensional liquid chromatography
Label-free cell phenotypic assays
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:
Chen, Si-Yue
;
Geng, Chang-An
;
Ma, Yun-Bao
;
Huang, Xiao-Yan
;
Yang, Xiao-Tong
收藏
  |  
浏览/下载:139/0
  |  
提交时间:2019/09/10
Gastrodia elata
Polybenzyls
Melatonin receptors
Structure-activity relationships
Docking study
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:
Geng, Chang-An
;
Yang, Tong-Hua
;
Huang, Xiao-Yan
;
Ma, Yun-Bao
;
Zhang, Xue-Mei
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/06/24
Uncaria rhynchophylla
Catechin
Melatonin receptors
Metabolites
Antidepressant activity
Adipogenic Activity of Oligomeric Hexafluoropropylene Oxide (Perfluorooctanoic Acid Alternative) through Peroxisome Proliferator-Activated Receptor gamma Pathway
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 卷号: 53, 期号: 6, 页码: 3287-3295
作者:
Li, Chuan-Hai
;
Ren, Xiao-Min
;
Guo, Liang-Hong
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  |  
浏览/下载:9/0
  |  
提交时间:2020/10/21
Synthesis and biological evaluation of novel potent FFA1 agonists containing 2,3-dihydrobenzo[b][1,4]dioxine
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 848-852
作者:
Kong, Deyu
;
Guo, Shimeng
;
Yang, Yushe
;
Guo, Bin
;
Xie, Xin
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
FFA1 agonist
2,3-Dihydrobenzo[b][1,4]dioxine
Insulin secretion
Type 2 diabetes mellitus
Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2019, 卷号: 59, 期号: 2, 页码: 842-857
作者:
Hou, Tingjun
;
Li, Youyong
;
Yu, Huidong
;
Li, Dan
;
Liu, Hui
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/06/24
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