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科研机构
上海药物研究所 [12]
内容类型
期刊论文 [12]
发表日期
2019 [12]
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发表日期:2019
专题:上海药物研究所
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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:
Huang, Ke
;
Liang, Qian
;
Zhou, Ye
;
Jiang, Lu-lu
;
Gu, Wei-ming
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2020/07/01
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH
期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 46, 页码: 7133-7145
作者:
Yang, Rui
;
Liu, Na
;
Chen, Ling
;
Jiang, Yiqun
;
Shi, Ying
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 14
作者:
Shi, Yulin
;
Fan, Songqing
;
Wu, Mengge
;
Zuo, Zhixiang
;
Li, Xingyang
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/01
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S))
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308
作者:
Shen, Jiayi
;
Zhang, Tao
;
Zhu, Su-Jie
;
Sun, Min
;
Tong, Linjiang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Farnesoid X Receptor Constructs an Immunosuppressive Microenvironment and Sensitizes (FXRPD)-P-high-L1(low) NSCLC to Anti-PD-1 Immunotherapy
期刊论文
CANCER IMMUNOLOGY RESEARCH, 2019, 卷号: 7, 期号: 6, 页码: 990-1000
作者:
You, Wenjie
;
Li, Lijun
;
Sun, Deqiao
;
Liu, Xueqing
;
Xia, Zongjun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
MiR-183-5p is required for non-small cell lung cancer progression by repressing PTEN
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 111, 页码: 1103-1111
作者:
Wang, Huimin
;
Ma, Zhongliang
;
Liu, Xiaomin
;
Zhang, Caiyan
;
Hu, Yanping
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
miR-183-5p
Non-small cell lung cancer
PTEN
Tumorigenesis
Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:
Niu, Ao
;
Wang, Yang
;
Yang, Yushe
;
Wei, Jianhai
;
Ding, Jian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
irreversible inhibitors
EGFR(T79014)( )mutant
anti-tumor
xenograft model
cell proliferation
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