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科研机构
上海药物研究所 [24]
内容类型
期刊论文 [24]
发表日期
2019 [24]
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共24条,第1-10条
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发表日期:2019
专题:上海药物研究所
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Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
In-depth profiling, characterization, and comparison of the ginsenosides among three different parts (the root, stem leaf, and flower bud) of Panax quinquefolius L. by ultra-high performance liquid chromatography/quadrupole-Orbitrap mass spectrometry
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 29, 页码: 7817-7829
作者:
Wang, Hongda
;
Zhang, Chunxia
;
Zuo, Tiantian
;
Li, Weiwei
;
Jia, Li
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
Panax quinquefolius
Ginsenoside
Q-Orbitrap
Mass defect filter
Metabolomics
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1604, 页码: 13
作者:
Yisimayili, Zainaipuguli
;
Abdulla, Rahima
;
Tian, Qiang
;
Wang, Yangyang
;
Chen, Mingcang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Punica granatum L. flowers
Polyphenols
Ellagitannin
Metabolism
HPLC-Q-TOF-MS2
A high-efficiency strategy integrating offline two-dimensional separation and data post-processing with dereplication: Characterization of bufadienolides in Venenum Bufonis as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1603, 页码: 179-189
作者:
Wei, Wenlong
;
Hou, Jinjun
;
Yao, Changliang
;
Bi, Qirui
;
Wang, Xia
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Offline two-dimensional liquid
chromatography
GNPS
High-efficiency
Dereplication
Bufadienolides of Venenum Bufonis
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:
Pintusophon, Salisa
;
Niu, Wei
;
Duan, Xiao-na
;
Olaleye, Olajide E.
;
Huang, Yu-hong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
ginsenoside
cytochrome P450 3A
organic anion-transporting polypeptide 1B3
herbal medicine-drug interactions
XueShuanTong
Panax notoginseng
Determining the protective effects of Yin-Chen-Hao Tang against acute liver injury induced by carbon tetrachloride using 16S rRNA gene sequencing and LC/MS-based metabolomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 567-577
作者:
Liu, Fang
;
Sun, Zhaolin
;
Hu, Pei
;
Tian, Qiang
;
Xu, Zhou
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Yin-Chen-Hao Tang
Liver injury
Metabolomics
Gut microbiota
LC-MS
Gene sequencing
Enantioselective determination of ketamine in dog plasma by chiral liquid chromatography-tandem mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 卷号: 33, 期号: 9, 页码: 8
作者:
Li, Ranran
;
Zhong, Kan
;
Jiang, Jinfang
;
Zhan, Yuan
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
chiral stationary phases
enantioselective LC-MS
MS
ketamine
stereoselective pharmacokinetics
Folic acid and its metabolite codetermination for pharmacokinetics with circadian rhythms and evaluation of oral bioavailability
期刊论文
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019, 页码: 10
作者:
Meng, Fanyue
;
Zhang, Guoqing
;
Wang, Caifen
;
Zhu, Rui
;
Li, Haiyan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
5-methyltetrahydrofolic acid
circadian rhythms
fasted plasma
folic acid
pharmacokinetics
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:
Pan, Lulu
;
Guo, Shuang
;
Chen, Xiaoyan
;
Jiang, Xiangrui
;
Shen, Jingshan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
TPNI71
Metabolism
UPLC/Q-TOF MS
High-resolution mass spectrometry
Metabolite identification
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