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Adenine derivatives invert high glucose-induced thioredoxin-interacting protein overexpression 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 6, 页码: 1998-2008
作者:  Zhong, Li;  Liu, Qing;  Ting, Yan Sie;  Vun Yien Thien;  Kalong, Nurwafa Syafiqah Binti
收藏  |  浏览/下载:89/0  |  提交时间:2019/01/08
Protective effect of ginsenoside metabolite compound K against diabetic nephropathy by inhibiting NLRP3 inflammasome activation and NF-kappa B/p38 signaling pathway in high-fat diet/streptozotocin-induced diabetic mice 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 63
作者:  Song, Wu;  Wei, Lin;  Du, Yanwei;  Wang, Yimei;  Jiang, Shuang
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
Dysregulated Txnip-ROS-Wnt axis contributes to the impaired ischemic heart repair in diabetic mice. 期刊论文
Biochimica et biophysica acta. Molecular basis of disease, 2018, 卷号: 1864, 页码: 3735-3745
作者:  Shen Mingzhi;  Bai Danna;  Liu Bei;  Lu Xiaozhao;  Hou Rongrong
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/19
Vitamin D-3 Protects against Diabetic Retinopathy by Inhibiting High-Glucose-Induced Activation of the ROS/TXNIP/NLRP3 Inflammasome Pathway 期刊论文
JOURNAL OF DIABETES RESEARCH, 2018
作者:  Lu, Li;  Lu, Qianyi;  Chen, Wei;  Li, Jingwen;  Li, Chunxia
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:  Han, Yachun;  Xu, Xiaoxuan;  Tang, Chengyuan;  Gao, Peng;  Chen, Xianghui
收藏  |  浏览/下载:29/0  |  提交时间:2019/12/03
ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ  
Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway 期刊论文
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2018
作者:  Zheng, Tao;  Yang, Xiaoyan;  Li, Wenjin;  Wang, Qibin;  Chen, Li
收藏  |  浏览/下载:2/0  |  提交时间:2019/11/26
TXNIP knockdown alleviates hepatocyte ischemia reperfusion injury through preventing p38/JNK pathway activation 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 502, 页码: 409-414
作者:  Zhang, Yong;  Miao, Liang-Sheng;  Cai, Ying-Min;  He, Jia-Xuan;  Zhang, Zhen-Ni
收藏  |  浏览/下载:2/0  |  提交时间:2019/11/26
c-Myc-driven glycolysis via TXNIP suppression is dependent on glutaminase-MondoA axis in prostate cancer 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 504, 页码: 415-421
作者:  Qu, Xuan;  Sun, Jing;  Zhang, Yami;  Li, Jun;  Hu, Junbi
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
Hypothermic oxygenated perfusion (HOPE) attenuates ischemia/reperfusion injury in the liver through inhibition of the TXNIP/NLRP3 inflammasome pathway in a rat model of donation after cardiac death 期刊论文
FASEB JOURNAL, 2018, 卷号: 32, 期号: 11
作者:  He, Weiyang;  Ye, Shaojun;  Zeng, Cheng;  Xue, Shuai;  Hu, Xiaoyan
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Li, Mingxin;  Zhang, Yemin;  Cao, Yingkang;  Zhang, Deling;  Liu, Le
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05


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