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Design and Synthesis of Marine Phidianidine Derivatives as Potential Immunosuppressive Agents 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 24, 页码: 11298-11308
作者:  Liu, Jin;  Li, Heng;  Chen, Kai-Xian;  Zuo, Jian-Ping;  Guo, Yue-Wei
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/01
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载:78/0  |  提交时间:2019/01/08
Comprehensive elucidation of the structural and functional roles of engineered disulfide bonds in antibody fc fragment 期刊论文
Journal of biological chemistry, 2018, 卷号: 293, 期号: 49, 页码: 19127-19135
作者:  Zeng, Fang;  Yang, Chunpeng;  Gao, Xinyu;  Li, Xuan;  Zhang, Zhe
收藏  |  浏览/下载:82/0  |  提交时间:2019/05/08
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu
收藏  |  浏览/下载:90/0  |  提交时间:2019/01/08
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian
收藏  |  浏览/下载:56/0  |  提交时间:2019/01/08
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang
收藏  |  浏览/下载:108/0  |  提交时间:2019/01/08
Synthesis of androgen receptor antagonists containing a pentafluorosulfanyl (SF5) moiety 期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 11
作者:  Jin, Jiyu;  Zhou, Yan;  Yang, Dehua;  Zhang, Qiumeng;  Wang, Ming-Wei
收藏  |  浏览/下载:69/0  |  提交时间:2019/01/08
Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9085-9104
作者:  Wang, Yuming;  Li, Lijun;  Fan, Jun;  Dai, Yang;  Jiang, Alan
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310
作者:  Peng, Jingjing;  Zhao, Lifen;  Wang, Lanlan;  Chen, Hui;  Qiu, Yunguang
收藏  |  浏览/下载:47/0  |  提交时间:2019/01/08


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