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PHLD融合蛋白在毕赤酵母中的构建和表达 期刊论文
生命科学研究, 2018, 卷号: 22, 期号: 2018年06期, 页码: 475-482
作者:  张新国;  郭广君;  李坤;  孙巧云;  郭思佳
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/13
Design and Synthesis of Marine Phidianidine Derivatives as Potential Immunosuppressive Agents 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 24, 页码: 11298-11308
作者:  Liu, Jin;  Li, Heng;  Chen, Kai-Xian;  Zuo, Jian-Ping;  Guo, Yue-Wei
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/01
Apoferritin nanocages loading mertansine enable effective eradiation of cancer stem-like cells in vitro 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2018, 卷号: 553, 期号: 1-2, 页码: 201-209
作者:  Tan, Tao;  Wang, Yuqi;  Wang, Hong;  Cao, Haiqiang;  Wang, Zhiwan
收藏  |  浏览/下载:137/0  |  提交时间:2019/01/08
Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan
收藏  |  浏览/下载:234/0  |  提交时间:2019/01/08
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载:78/0  |  提交时间:2019/01/08
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08
Characteristics of hERG and hNav1.5 channel blockade by sulcardine sulfate, a novel anti-arrhythmic compound 期刊论文
European journal of pharmacology, 2018, 卷号: 844, 页码: 130-138
作者:  Chen, Weihai;  Gan, Lu;  Wang, Yiping
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui
收藏  |  浏览/下载:135/0  |  提交时间:2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/11


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