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Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:  Gong, Grace Qun;  Wang, Ke;  Dai, Xin-Chuan;  Zhou, Yan;  Basnet, Rajesh
收藏  |  浏览/下载:98/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载:87/0  |  提交时间:2019/01/08
Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells 期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 10, 页码: 3131-3147
作者:  Wan, Bin;  Xin, Yan;  Yang, Yu;  Cui, Xue-Jing;  Xie, Yi-Chun
收藏  |  浏览/下载:39/0  |  提交时间:2019/06/20
Secretogranin-II plays a critical role in zebrafish neurovascular modeling 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2018, 卷号: 10, 期号: 5, 页码: 388-401
作者:  Tao, Binbin;  Hu, Hongling;  Mitchell, Kimberly;  Chen, Ji;  Jia, Haibo
收藏  |  浏览/下载:36/0  |  提交时间:2019/07/01
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Steroidal alkaloid solanine A from Solanum nigrum Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon gamma-activated murine macrophages and animal models of inflammation 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 105, 期号: 2018, 页码: 606-615
作者:  Zhao, Lin;  Wang, Lun;  Di, Suo-ni;  Xu, Qian;  Ren, Qing-cuo
收藏  |  浏览/下载:8/0  |  提交时间:2020/12/24
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/10
Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 8, 页码: 782-792
作者:  Yu, Dandan;  Zhang, Yong;  Chen, Gege;  Xie, Yongsheng;  Xu, Zhijian
收藏  |  浏览/下载:52/0  |  提交时间:2019/01/08


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