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Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 8, 页码: 782-792
作者:  Yu, Dandan;  Zhang, Yong;  Chen, Gege;  Xie, Yongsheng;  Xu, Zhijian
收藏  |  浏览/下载:52/0  |  提交时间:2019/01/08
Anticancer activity of safranal against colon carcinoma is due to induction of apoptosis and G2/M cell cycle arrest mediated by suppression of mTOR/PI3K/Akt pathway 期刊论文
JOURNAL OF BUON, 2018, 卷号: 23, 期号: 3, 页码: 574-578
作者:  Zhang, Yibing;  Zhao, Yong;  Guo, Jianyou;  Cui, Haifeng;  Liu, Sha
收藏  |  浏览/下载:39/0  |  提交时间:2018/08/14
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy 期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:  Guo, Xiaodan;  Lv, Jianlu;  Lu, Jian;  Fan, Lei;  Huang, Xi
收藏  |  浏览/下载:54/0  |  提交时间:2019/01/08
Sanguinarine inhibits epithelial ovarian cancer development via regulating long non-coding RNA CASC2-EIF4A3 axis and/or inhibiting NF-kappa B signaling or PI3K/AKT/mTOR pathway 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 102
作者:  Zhang, Suxian;  Leng, Tianyan;  Zhang, Qin;  Zhao, Qinghua;  Nie, Xiaofeng
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/04
自噬通路相关调节基因与甲状腺癌 期刊论文
中国医药指南, 2018, 卷号: 16, 期号: 7
作者:  普梦娴;  柯亭羽
收藏  |  浏览/下载:18/0  |  提交时间:2019/12/04
TRIM22 knockdown suppresses chronic myeloid leukemia via inhibiting PI3K/Akt/mTOR signaling pathway 期刊论文
CELL BIOLOGY INTERNATIONAL, 2018, 卷号: 42, 期号: 9
作者:  Li, Liyin;  Qi, Yanhua;  Ma, Xiaobo;  Xiong, Guosheng;  Wang, Lijun
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/04
Ligustrazine Inhibits Growth, Migration and Invasion of Medulloblastoma Daoy Cells by Up-Regulation of miR-211 期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 卷号: 49, 期号: 5
作者:  Zhao, Conghai;  Li, Dongyuan;  Xu, Donghui;  Chi, Guonan
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-kappa B and PI3K/Akt/mTOR pathways 期刊论文
MOLECULAR IMMUNOLOGY, 2018, 卷号: 94
作者:  Zhao, Guoqing;  Meng, Lu;  Li, Longyun;  Lu, Shan;  Li, Kai
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05


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