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CORC

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Enhanced interaction between SEC2 mutant and TCR V induces MHC II-independent activation of T cells via PKC/NF-B and IL-2R/STAT5 signaling pathways 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 51, 页码: 19771-19784
作者:  Fu, Xuanhe;  Xu, Mingkai;  Song, Yubo;  Li, Yongqiang;  Zhang, Huiwen
收藏  |  浏览/下载：64/0  |  提交时间：2019/06/04
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Natural flavonoid galangin alleviates microglia-trigged blood-retinal barrier dysfunction during the development of diabetic retinopathy 期刊论文
The Journal of nutritional biochemistry, 2018, 卷号: 65, 页码: 1-14
作者:  Zhang, Tianyu;  Mei, Xiyu;  Ouyang, Hao;  Lu, Bin;  Yu, Zengyang
收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08
Different roles of insulin receptor a and b in maintaining blood glucose homeostasis in zebrafish 期刊论文
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2018, 卷号: 269, 页码: 33-45
作者:  Gong, Yulong;  Zhai, Gang;  Su, Jingzhi;  Yang, Binyuan;  Jin, Junyan
收藏  |  浏览/下载：62/0  |  提交时间：2019/07/01
ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia 期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264
作者:  Zhou, Tingting;  Du, Mengfan;  Zhao, Tong;  Quan, Lingling;  Zhu, Zhiyuan
收藏  |  浏览/下载：94/0  |  提交时间：2019/01/08
Targeting Nrf2-mediated heme oxygenase-1 enhances non-thermal plasma-induced cell death in non-small-cell lung cancer A549 cells 期刊论文
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 658, 页码: 54-65
作者:  Ma, Jie;  Yu, K. N.;  Cheng, Cheng;  Ni, Guohua;  Shen, Jie
收藏  |  浏览/下载：51/0  |  提交时间：2019/01/11
Scutellarin alleviates blood-retina-barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy 期刊论文
Biochemical pharmacology, 2018, 卷号: 159, 页码: 82-95
作者:  Mei, Xiyu;  Zhang, Tianyu;  Ouyang, Hao;  Lu, Bin;  Wang, Zhengtao
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:  Li, R.;  Du, Y.;  Shen, J.
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1768-1776
作者:  Liu, Ying-Qiang;  Wang, Ya-Nan;  Lu, Xiao-Yun;  Tong, Lin-Jiang;  Li, Yan
收藏  |  浏览/下载：110/0  |  提交时间：2019/01/08
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08

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