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CORC

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The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui
收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Different roles of insulin receptor a and b in maintaining blood glucose homeostasis in zebrafish 期刊论文
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2018, 卷号: 269, 页码: 33-45
作者:  Gong, Yulong;  Zhai, Gang;  Su, Jingzhi;  Yang, Binyuan;  Jin, Junyan
收藏  |  浏览/下载：64/0  |  提交时间：2019/07/01
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08
Targeting Nrf2-mediated heme oxygenase-1 enhances non-thermal plasma-induced cell death in non-small-cell lung cancer A549 cells 期刊论文
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 658, 页码: 54-65
作者:  Ma, Jie;  Yu, K. N.;  Cheng, Cheng;  Ni, Guohua;  Shen, Jie
收藏  |  浏览/下载：51/0  |  提交时间：2019/01/11
Scutellarin alleviates blood-retina-barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy 期刊论文
Biochemical pharmacology, 2018, 卷号: 159, 页码: 82-95
作者:  Mei, Xiyu;  Zhang, Tianyu;  Ouyang, Hao;  Lu, Bin;  Wang, Zhengtao
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:  Li, R.;  Du, Y.;  Shen, J.
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang
收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08
A 20(S)-protopanaxadiol derivative PPD12 reverses ABCB1-mediated multidrug resistance with oral bioavailability and low toxicity 期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 5, 页码: 5891-5899
作者:  Wei, Shunfeng;  Chen, Wantao;  Hu, Lihong;  Pan, Jinsong;  Wang, Xu
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9085-9104
作者:  Wang, Yuming;  Li, Lijun;  Fan, Jun;  Dai, Yang;  Jiang, Alan
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08

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