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CORC

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Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery 期刊论文
SMALL, 2018, 卷号: 14, 期号: 47
作者:  Yin, Weimin;  Yu, Xiaolu;  Kang, Xuejia;  Zhao, Yuge;  Zhao, Pengfei
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang
收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08
Arsenic circumvents the gefitinib resistance by binding to P62 and mediating autophagic degradation of EGFR in non-small cell lung cancer 期刊论文
CELL DEATH & DISEASE, 2018, 卷号: 9
作者:  Mao, Jianhua;  Ma, Lie;  Shen, Yan;  Zhu, Kongkai;  Zhang, Ru
收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:  Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Tong, Yi;  Sun, Deheng
收藏  |  浏览/下载：61/0  |  提交时间：2019/01/08
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306
作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong
收藏  |  浏览/下载：77/0  |  提交时间：2019/01/08
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439
作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan
收藏  |  浏览/下载：70/0  |  提交时间：2019/01/08
Allenamide as a bioisostere of acrylamide in the design and synthesis of targeted covalent inhibitors 期刊论文
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 2, 页码: 244-253
作者:  Chen, Deheng;  Guo, Dexiang;  Yan, Ziqin;  Zhao, Yujun
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Efficacy and Safety of Osimertinib in EGFR T790M-Positive Advanced NSCLC Patients with Brain Metastases (APOLLO Study) 会议论文
作者:  Xing, L.;  Pan, Y.;  Shi, Y.;  Shu, Y.;  Feng, J.
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152
作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/05
Pharmacokinetics of Osimertinib in Chinese Patients With Advanced NSCLC: A Phase 1 Study 期刊论文
JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 卷号: 58, 期号: 4
作者:  Zhao, Hongyun;  Cao, Junning;  Chang, Jianhua;  Zhang, Zhenxian;  Yang, Li
收藏  |  浏览/下载：31/0  |  提交时间：2019/12/05

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