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CORC

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Amino Acid Coordination Driven Self-Assembly for Enhancing both the Biological Stability and Tumor Accumulation of Curcumin 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 52, 页码: 17084-17088
作者:  Li, Yongxin;  Zou, Qianli;  Yuan, Chengqian;  Li, Shukun;  Xing, Ruirui
收藏  |  浏览/下载：41/0  |  提交时间：2019/04/03
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2018, 卷号: 138, 期号: 4, 页码: 247-256
作者:  Yao, Xingang;  Guo, Songxin;  Wu, Wenyu;  Wang, Jinan;  Wu, Shengen
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Adenine derivatives invert high glucose-induced thioredoxin-interacting protein overexpression 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 6, 页码: 1998-2008
作者:  Zhong, Li;  Liu, Qing;  Ting, Yan Sie;  Vun Yien Thien;  Kalong, Nurwafa Syafiqah Binti
收藏  |  浏览/下载：89/0  |  提交时间：2019/01/08
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294
作者:  Xing, Jing;  Zhang, Rukang;  Jiang, Xiangrui;  Hu, Tianwen;  Wang, Xinjun
收藏  |  浏览/下载：86/0  |  提交时间：2019/01/08
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian
收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:  Li, R.;  Du, Y.;  Shen, J.
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08

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