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上海药物研究所 [10]
大连化学物理研究所 [5]
化学研究所 [4]
湖南大学 [4]
武汉大学 [2]
成都中医药大学 [2]
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期刊论文 [41]
发表日期
2018 [41]
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Pharmacolo... [1]
地球科学::地理学 [1]
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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Discovery of beta(2)-adrenoceptor agonists in Curcuma zedoaria Rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1577, 页码: 59-65
作者:
Liu, Yanfang
;
Liang, Xinmiao
;
Zhou, Weijia
;
Wang, Jixia
;
Zhao, Yaopeng
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/06/20
Curcuma zedoaria Rosc
beta(2)-adrenoceptor agonists
Diarylheptanoids
Label-free cell phenotypic assay
Two-dimensional liquid chromatography
Discovery of beta(2)-adrenoceptor agonists in curcuma zedoaria rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography
期刊论文
Journal of chromatography a, 2018, 卷号: 1577, 页码: 59-65
作者:
Zhou, Weijia
;
Wang, Jixia
;
Zhao, Yaopeng
;
Yu, Long
;
Fang, Ye
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/05/08
Curcuma zedoaria rosc
Beta(2)-adrenoceptor agonists
Diarylheptanoids
Label-free cell phenotypic assay
Two-dimensional liquid chromatography
Implementation of a Single Quadrupole Mass Spectrometer for Fingerprint Analysis: Venenum bufonis as a Case Study
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 11
作者:
Wei, Wenlong
;
Wang, Xia
;
Hou, Jinjun
;
Yao, Changliang
;
Feng, Zijin
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/01/08
mass spectrometry fingerprint
Venenum bufonis
quality control
chemometrics analysis
Characterization and discrimination of steroidal saponins in Tribulus terrestris L. and its three different aerial parts by chemical profiling with chemometrics analysis
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2018, 卷号: 41, 期号: 22
作者:
Qi, Peng
;
Zheng, Yuanyuan
;
Shen, Yao
;
Wang, Jianwei
;
Bi, Qirui
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/01/08
partial least squares discriminant analysis
steroidal saponins
support vector machines
traditional Chinese medicine
Tribulus terrestris L
A new class of HIV-1 inhibitors and the target identification via proteomic profiling
期刊论文
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 11, 页码: 1430-1439
作者:
Ge, Ying-Zi
;
Zhou, Bin
;
Xiao, Ruo-Xuan
;
Yuan, Xiao-Jing
;
Zhou, Hu
收藏
  |  
浏览/下载:183/0
  |  
提交时间:2019/01/08
ergostane-type steroids
anti-HIV
target identification
PKM2
Clay minerals and isotopes of Pleistocene lacustrine sediments from the western Qaidam Basin, NE Tibetan Plateau
期刊论文
APPLIED CLAY SCIENCE, 2018, 卷号: 162, 期号: 0, 页码: 382-390
作者:
Li, MH (Li, Minghui)
;
Sun, SR (Sun, Shurui)
;
Fang, XM (Fang, Xiaomin)
;
Wang, CH (Wang, Chunhong)
;
Wang, ZR (Wang, Zhengrong)
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  |  
浏览/下载:30/0
  |  
提交时间:2019/05/21
Core Sg-1
Illite-smectite
Paleoclimatic Interpretation
Evaporite Minerals
Geothermal Systems
Tectonic Uplift
New-zealand
Long Core
China
Record
Target discovery of ebselen with a biotinylated probe
期刊论文
CHEMICAL COMMUNICATIONS, 2018, 卷号: 54, 期号: 68, 页码: 9506-9509
作者:
Chen, Zhenzhen
;
Jiang, Zhongyao
;
Chen, Nan
;
Shi, Qian
;
Tong, Lili
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/09
An enhanced strategy integrating offline two-dimensional separation and step-wise precursor ion list-based raster-mass defect filter: Characterization of indole alkaloids in five botanical origins of Uncariae Ramulus Cum Unicis as an exemplary application
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1563, 页码: 124-134
作者:
Pan, Huiqin
;
Yao, Changliang
;
Yang, Wenzhi
;
Yao, Shuai
;
Huang, Yong
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Offline comprehensive 2D LC
Precursor ion list
Mass defect filter
Uncariae Ramulus Cum Unicis
Indole alkaloid
Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 26, 页码: E5896-E5905
作者:
Dai, Jianye
;
Liang, Kai
;
Zhao, Shan
;
Jia, Wentong
;
Liu, Yuan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/04/09
Baicalin
Cpt1
Obesity
Chemical Proteomics
Steatosis
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