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CORC

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Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors 期刊论文
Cell reports, 2018, 卷号: 25, 期号: 13, 页码: 3582-3590.e4
作者:  Zhang, Jin-Bao;  Chang, Shenghai;  Xu, Pan;  Miao, Miao;  Wu, Hangjun
收藏  |  浏览/下载：115/0  |  提交时间：2019/01/08
Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy 期刊论文
Nanoscale, 2018
作者:  Chang, Ya;  Yao, Shuo;  Chen, Yifang;  Huang, Jingjing;  Wu, Aihua
收藏  |  浏览/下载：75/0  |  提交时间：2019/01/08
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609
作者:  Chen, Danqi;  Chen, Yuehong;  Lian, Fulin;  Chen, Liu;  Li, Yanlian
收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08
Reaction Mechanisms of Well-Defined Metal-N-4 Sites in Electrocatalytic CO2 Reduction 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 50, 页码: 16339-16342
作者:  Zhang, Zheng;  Xiao, Jianping;  Chen, Xue-Jiao;  Yu, Song;  Yu, Liang
收藏  |  浏览/下载：51/0  |  提交时间：2019/06/20
Reaction mechanisms of well-defined metal-n-4 sites in electrocatalytic co2 reduction 期刊论文
Angewandte chemie-international edition, 2018, 卷号: 57, 期号: 50, 页码: 16339-16342
作者:  Zhang, Zheng;  Xiao, Jianping;  Chen, Xue-Jiao;  Yu, Song;  Yu, Liang
收藏  |  浏览/下载：75/0  |  提交时间：2019/05/08
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions 期刊论文
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2018, 卷号: 98, 期号: 8, 页码: 2039-2048
作者:  Zhang, Libin;  Feng, Qiming;  Ding, Kui;  Sun, Lina;  Huo, Da
收藏  |  浏览/下载：30/0  |  提交时间：2019/07/15

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