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浏览/检索结果: 共27条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice 期刊论文 Cerebral cortex (New York, N.Y. : 1991), 2018 作者:  Shen, Mengxin;  Lv, Dan;  Li, Shuting;  Zhang, Yanhua;  Wang, Zhen 收藏  |  浏览/下载：104/0  |  提交时间：2019/01/08 ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia 期刊论文 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264 作者:  Zhou, Tingting;  Du, Mengfan;  Zhao, Tong;  Quan, Lingling;  Zhu, Zhiyuan 收藏  |  浏览/下载：94/0  |  提交时间：2019/01/08 beta cell  apoptosis  glucose-stimulated insulin secretion  T2DM   Modified citrus pectin inhibited bladder tumor growth through downregulation of galectin-3 期刊论文 Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1885-1893 作者:  Fang, Tian;  Liu, Dan-Dan;  Ning, He-Ming;  Sun, Jing-Ya;  Huang, Xiao-Jing 收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08 Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds 期刊论文 Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912 作者:  Gong, Grace Qun;  Wang, Ke;  Dai, Xin-Chuan;  Zhou, Yan;  Basnet, Rajesh 收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 MiR-4465 directly targets PTEN to inhibit AKT/mTOR pathway-mediated autophagy 期刊论文 Cell stress & chaperones, 2018 作者:  Tao, Zhouteng;  Feng, Chenxi;  Mao, Chenmei;  Ren, Jin;  Tai, Yusi 收藏  |  浏览/下载：75/0  |  提交时间：2019/01/08 Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文 Chemical biology & drug design, 2018 作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways 期刊论文 FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9 作者:  Tang, Dan;  Liu, Liu;  Ajiakber, Dildar;  Ye, Jianping;  Xu, Jianjun 收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08 type 2 diabetes mellitus  Punica granatum L. flower  anti-diabetic herb  oral glucose tolerance test  endoplasmic reticulum stress  insulin resistance   Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia 收藏  |  浏览/下载：87/0  |  提交时间：2019/01/08 Anticancer drug  Phosphatidylinositol 3-kinase  Structure-activity relationship   Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Proliferation  Anticancer drug  Phosphatidylinositol 3-kinase inhibitor  Apoptosis  Structure-activity relationship   Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文 ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771 作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 SGK  AKT  PI3K  Cancer  Signalling: Kinase  Inhibitor