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科研机构
湖南中医药大学 [2]
厦门大学 [1]
上海药物研究所 [1]
中南大学 [1]
内容类型
期刊论文 [4]
学位论文 [1]
发表日期
2017 [5]
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Appoptosin的促凋亡作用及其在帕金森氏病中的功能研究
学位论文
2017, 2015
李远方
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浏览/下载:2/0
  |  
提交时间:2017/06/20
appoptosin
凋亡
帕金森氏病
appoptosin
apoptosis
Parkinson’s disease
Amentoflavone protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through PI3K/Akt and ERK signaling pathways
期刊论文
Toxicology and applied pharmacology, 2017, 卷号: 319, 页码: 80-90
作者:
Cao, Qin
;
Qin, Liyue
;
Huang, Fei
;
Wang, Xiaoshuang
;
Yang, Liu
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浏览/下载:22/0
  |  
提交时间:2019/01/08
Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 6, 页码: 1359-1370
作者:
Zhao, Fanpeng
;
Wang, Wenzhang
;
Wang, Chunyu
;
Siedlak, Sandra L.
;
Fujioka, Hisashi
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浏览/下载:2/0
  |  
提交时间:2019/12/03
DA
dopaminergic
DIV
days in vitro
DLP1
dynamin-like protein 1
4-HNE
4-hydroxynonenal
JNKs
c-Jun N-terminal kinases
MPTP
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MAP2
microtubule-associated protein-2
Fis1
mitochondrial fission 1
Mff
mitochondrial fission factor
Mfn2
mitofusin 2
MMP
mitochondrial membrane potential
Mfn1/2
mitofusin 1/2
OPA1
optic atrophy 1
PQ
paraquat
PD
Parkinson's disease
ROS
reactive oxygen species
SN
substantia nigra pars compacta
TMRM
tetramethylrhodamine methyl ester
TH
tyrosine hydroxylase
Tg
transgenic
Mitochondrial dynamics
DLP1
Drp1
Mfn2
Paraquat
Parkinson's disease
DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult
期刊论文
Toxicology Letters, 2017, 卷号: 271, 期号: Volume 271, 页码: 74-83
作者:
Zhang, Xiao-Ling
;
Yuan, Yu-He
;
Shao, Qian-Hang
;
Wang, Zhen-Zhen
;
Zhu, Cheng-Gen
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浏览/下载:14/0
  |  
提交时间:2019/12/27
8-OHdG
8-hydroxygluanine
ARE
antioxidant response element
GSK3β
glycogen synthase kinase 3β
HO-1
hemeoxygenase-1
LDH
lactate dehydrogenase
MDA
malondialdehyde
NQO1
NADPH quinone oxidoreductase 1
Nrf2
nuclear factor erythroid 2-related factor
PI3K
phosphoinositide-3-kinase
PD
Parkinson’s disease
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TCMs
traditional Chinese medicines
20C
Parkinson’s disease (PD)
DJ-1
Akt
Oxidative stress
Nuclear factor erythroid 2-related factor (Nrf2)
Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome
期刊论文
International Immunopharmacology, 2017, 卷号: 49, 页码: 155-160
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Yang, Peng-fei
;
Yuan, Yu-he*
;
Chen, Nai-hong*
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浏览/下载:4/0
  |  
提交时间:2019/12/27
AD
Alzheimer's disease
ANSC
adult neural stem cell
Aβ
amyloid-β protein
CNS
central nervous system
DAMPs
danger-associated molecular patterns
IL-1
interleukin-1
LBs
Lewy bodies
NFTs
neurofibrillary tangles
NLRs
NOD-like receptors
PAMPs
pathogen-associated molecular patterns
PD
Parkinson's disease
PRRs
pattern recognition receptors
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TLRs
toll-like receptors
α-Synuclein
Amyloid-β
Inflammation
NLRP3 inflammasome
Neurodegenerative disease
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