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CORC

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6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 12, 页码: 5453-5465
作者:  Liu, Yanning;  Lou, Guohua;  Norton, John T.;  Wang, Chen;  Kandela, Irawati
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266
作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08
Phase Evolution of VO2 Polymorphs during Hydrothermal Treatment in the Presence of AOT 期刊论文
CRYSTAL GROWTH & DESIGN, 2017, 卷号: 17, 期号: 11, 页码: 5927-5934
作者:  Zhong, Li;  Li, Kaibin;  Luo, Yuanyuan;  Li, Ming;  Wang, Hua
收藏  |  浏览/下载：31/0  |  提交时间：2019/06/17
Towards the modulation of oxidative damage, apoptosis and tight junction protein in response to dietary leucine deficiency: A likely cause of ROS-induced gill structural integrity impairment 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 70, 期号: 1, 页码: 609-620
作者:  Jiang, Wei-Dan;  Deng, Yu-Ping;  Zhou, Xiao-Qiu;  Liu, Yang;  Jiang, Jun
收藏  |  浏览/下载：18/0  |  提交时间：2019/07/03
Dietary pyridoxine deficiency reduced growth performance and impaired intestinal immune function associated with TOR and NF-kappa B signalling of young grass carp (Ctenopharyngodon idella) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 70, 期号: 1, 页码: 682-700
作者:  Zheng, Xin;  Feng, Lin;  Jiang, Wei-Dan;  Wu, Pei;  Liu, Yang
收藏  |  浏览/下载：28/0  |  提交时间：2019/07/03
Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542
作者:  Xie, Qin;  Chen, Hui;  Ai, Jing;  Gao, Ying-lei;  Geng, Mei-yu
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 20, 页码: 8407-8424
作者:  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Wu, Hong;  Qi, Ziping
收藏  |  浏览/下载：42/0  |  提交时间：2019/06/17
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697
作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan
收藏  |  浏览/下载：711/0  |  提交时间：2018/08/17

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