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Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun
收藏  |  浏览/下载：136/0  |  提交时间：2019/01/08
Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157
作者:  Wang, Wen-Long;  Chen, Xiao-Yu;  Gao, Ya;  Gao, Li-Xin;  Sheng, Li
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat 期刊论文
NANO LETTERS, 2017, 卷号: 17, 期号: 12, 页码: 7684-7690
作者:  Peng, Huige;  Chen, Binfan;  Huang, Wei;  Tang, Yubo;  Jiang, Yifan
收藏  |  浏览/下载：65/0  |  提交时间：2019/01/08
Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Dihydroartemisinin selectively inhibits PDGFR alpha-positive ovarian cancer growth and metastasis through inducing degradation of PDGFR alpha protein 期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:  Li, Xiaoguang;  Ba, Qian;  Liu, Yanling;  Yue, Qingxi;  Chen, Peizhan
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文
FRONTIERS IN CHEMISTRY, 2017, 卷号: 5
作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia
收藏  |  浏览/下载：60/0  |  提交时间：2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08
Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1 期刊论文
ACTA PHARMACEUTICA SINICA B, 2017, 卷号: 7, 期号: 6, 页码: 657-664
作者:  Cheng, Xuewei;  Lv, Xia;  Qu, Hengyan;  Li, Dandan;  Hu, Mengmeng
收藏  |  浏览/下载：27/0  |  提交时间：2019/06/20
A Novel Vascular Endothelial Growth Factor Receptor Participates in White Spot Syndrome Virus Infection in Litopenaeus vannamei 期刊论文
FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8
作者:  Li, Shihao;  Wang, Zhiwei;  Li, Fuhua;  Yu, Kuijie;  Xiang, Jianhai
收藏  |  浏览/下载：29/0  |  提交时间：2018/01/11
Facile Synthesis of Novel Perfluorocarbon-Modulated 4-Anilinoquinazoline Analogues 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 11, 页码: 1693-1700
作者:  Shi, Huiping;  Lai, Bonan;  Chen, Shizhen;  Zhou, Xin
收藏  |  浏览/下载：64/0  |  提交时间：2018/11/05

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