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科研机构
上海药物研究所 [3]
复旦大学上海医学院 [2]
上海中医药大学 [2]
西安交通大学 [1]
上海大学 [1]
中国医学科学院 北京... [1]
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期刊论文 [10]
发表日期
2017 [10]
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Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:
Shao, Li-Dong
;
Bao, Ying
;
Shen, Yu
;
Su, Jia
;
Leng, Ying
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
11 beta-HSD1 inhibitor
Hupehenols
Dammarane
SAR
Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 2
作者:
Zhang, Qi
;
Pu, Yiqiong
;
Wang, Bing
;
Wang, Yuqin
;
Dong, Tina Tingxia
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
20(S)-protopanaxadiol
solid dispersion
polymer
molecular docking
in vitro dissolution
UHPLC-Q-TOF-MS-based metabolomics approach to compare the saponin compositions of Xueshuantong injection and Xuesaitong injection
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2017, 卷号: 40, 期号: 4, 页码: 834-841
作者:
Yao, Changliang
;
Yang, Wenzhi
;
Zhang, Jingxian
;
Qiu, Shi
;
Chen, Ming
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
metabolomics
notoginseng saponins
traditional Chinese medicine
Xuesaitong
Xueshuantong
Protopanaxadiol and metformin synergistically inhibit estrogen-mediated proliferation and anti-autophagy effects in endometrial cancer cells
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2017, 卷号: 9, 期号: 9
作者:
Gu, Chun-Jie
;
Cheng, Jiao
;
Zhang, Bing
;
Yang, Shao-Liang
;
Xie, Feng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
metformin
protopanaxadiol
estrogen
endometrial cancer cells
growth
autophagy
Restricted access magnetic core-mesoporous shell microspheres with C8-modified interior pore walls for the identification of 20(S)-protopanaxadiol metabolites in rat plasma using UPLC-Q-TOF-MS/MS
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017, 卷号: 1054
作者:
Ling, Jin
;
Yu, Yingjia
;
Feng, Jianan
;
Xu, Changjiang
;
Jiang, Jiebing
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
20(8)-Protopanaxadiol
Metabolite
C8-modified interior pore-walls
UPLC-Q-TOF
Restricted access material
20(S)-Protopanaxadiol enhances angiogenesis via HIF-1 alpha-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice
期刊论文
EXPERIMENTAL AND MOLECULAR MEDICINE, 2017, 卷号: 49
作者:
Zhang, Er-Yun
;
Gao, Bo
;
Shi, Hai-Lian
;
Huang, Ling-Fang
;
Yang, Li
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 2
作者:
Dong, Tina Tingxia
;
Zhang, Qi
;
Pu, Yiqiong
;
Wang, Bing
;
Wang, Yuqin
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
20(S)-protopanaxadiol
solid dispersion
polymer
molecular docking
in vitro dissolution
Protopanaxadiol and Protopanaxatriol-Type Saponins Ameliorate Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus in High-Fat Diet/Streptozocin-Induced Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Deng, Jianjun
;
Liu, Yao
;
Duan, Zhiguang
;
Zhu, Chenhui
;
Hui, Junfeng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
protopanaxatriol-type saponins
type 2 diabetes mellitus
lipid metabolism
protopanaxadiol-type saponins
inflammation
glucose metabolism
20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice
期刊论文
Experimental & molecular medicine, 2017, 卷号: 49, 页码: e387
作者:
Zhang Er-Yun[1]
;
Gao Bo[2]
;
Shi Hai-Lian[3]
;
Huang Ling-Fang[4]
;
Yang Li[5]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/04/26
Cytochromes P450 Inhibitory Excipient-Based Self-Microemulsions for the Improved Bioavailability of Protopanaxatriol and Protopanaxadiol: Preparation and Evaluation
期刊论文
2017, 卷号: 83, 期号: 5, 页码: 453-460
作者:
Yang, Feifei
;
Zhou, Jing
;
Liu, Chunyu
;
Hu, Xiao
;
Pan, Ruile
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/04
protopanaxatriol (PPT)
protopanaxadiol (PPD)
self-microemulsion
CYP450
oral bioavailability
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