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Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun
收藏  |  浏览/下载：136/0  |  提交时间：2019/01/08
Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990
作者:  Xie, Chengying;  Chen, Xiangling;  Zheng, Mingyue;  Liu, Xiaohong;  Wang, Hongbin
收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08
Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat 期刊论文
NANO LETTERS, 2017, 卷号: 17, 期号: 12, 页码: 7684-7690
作者:  Peng, Huige;  Chen, Binfan;  Huang, Wei;  Tang, Yubo;  Jiang, Yifan
收藏  |  浏览/下载：66/0  |  提交时间：2019/01/08
Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08
Dietary pyridoxine deficiency reduced growth performance and impaired intestinal immune function associated with TOR and NF-kappa B signalling of young grass carp (Ctenopharyngodon idella) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 70, 期号: 1, 页码: 682-700
作者:  Zheng, Xin;  Feng, Lin;  Jiang, Wei-Dan;  Wu, Pei;  Liu, Yang
收藏  |  浏览/下载：28/0  |  提交时间：2019/07/03
Metal-carbenicillin framework-based nanoantibiotics with enhanced penetration and highly efficient inhibition of mrsa 期刊论文
Biomaterials, 2017, 卷号: 144, 页码: 155-165
作者:  Duan, Fei;  Feng, Xiaochen;  Jin, Yan;  Liu, Dawei;  Yang, Xinjian
收藏  |  浏览/下载：51/0  |  提交时间：2019/04/23
Blocking gp130 signaling suppresses autotaxin expression in adipocytes and improves insulin sensitivity in diet-induced obesity 期刊论文
JOURNAL OF LIPID RESEARCH, 2017, 卷号: 58, 期号: 11, 页码: 2102-2113
作者:  Sun, Shuhong;  Wang, Ran;  Song, Jianwen;  Guan, Ming;  Li, Na
收藏  |  浏览/下载：18/0  |  提交时间：2018/04/25
Overcoming resistance to cisplatin by inhibition of glutathione s-transferases (gsts) with ethacraplatin micelles in vitro and in vivo 期刊论文
Biomaterials, 2017, 卷号: 144, 页码: 119-129
作者:  Li, Shuyi;  Li, Chan;  Jin, Shubin;  Liu, Juan;  Xue, Xiangdong
收藏  |  浏览/下载：48/0  |  提交时间：2019/04/23
Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review 期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11
作者:  Shah, Sayed Asmat Ali;  Akhter, Najeeb;  Auckloo, Bibi Nazia;  Khan, Ishrat;  Lu, Yanbin
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08

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