CORC

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CORC

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Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361
作者:  Jiang, Hao;  Xing, Jing;  Wang, Chen;  Zhang, Hao;  Yue, Liyan
收藏  |  浏览/下载：110/0  |  提交时间：2019/01/08
JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 49, 页码: 86312-86324
作者:  Wang, Huogang;  Hong, Bo;  Li, Xuemin;  Deng, Ke;  Li, Hong
收藏  |  浏览/下载：25/0  |  提交时间：2018/08/17
Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195
作者:  Hu, Jianping;  Wang, Yingqing;  Li, Yanlian;  Xu, Lin;  Cao, Danyan
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017, 卷号: 57, 期号: 7, 页码: 1677-1690
作者:  Xing, Jing;  Lu, Wenchao;  Liu, Rongfeng;  Wang, Yulan;  Xie, Yiqian
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay 期刊论文
MEDCHEMCOMM, 2017, 卷号: 8, 期号: 6, 页码: 1322-1331
作者:  Chen, Zhifeng;  Zhang, Hao;  Liu, Shien;  Xie, Yiqian;  Jiang, Hao
收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08
Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 9, 页码: 3887-3901
作者:  Zhao, Yujun;  Bai, Longchuan;  Liu, Liu;  McEachern, Donna;  Stuckey, Jeanne A.
收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08
HAL2 overexpression induces iron acquisition in bdf1 Delta cells and enhances their salt resistance 期刊论文
CURRENT GENETICS, 2017, 卷号: 63, 期号: 2, 页码: 229-239
作者:  
收藏  |  浏览/下载：33/0  |  提交时间：2017/06/21
Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 9, 页码: 2003-2009
作者:  Sun, Zhongya;  Zhang, Hao;  Chen, Zhifeng;  Xie, Yiqian;  Jiang, Hao
收藏  |  浏览/下载：89/0  |  提交时间：2019/01/08
Discovery of a new class of highly potent small-molecule degraders of BET bromodomain proteins 会议论文
作者:  Xu, Fuming;  Hu, Jiantao;  Zhou, Bing;  Chen, Zhuo;  Lin, Mei
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 11
作者:  Cheung, Kalung;  Lu, Geming;  Sharma, Rajal;  Vincek, Adam;  Zhang, Ruihua
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05

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