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浏览/检索结果: 共29条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 24, 页码: 10231-10244 作者:  Liu, Qiufeng;  Huang, Fubao;  Yuan, Xiaojing;  Wang, Kai;  Zou, Yi 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270 作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing;  Xie, Yi-qian 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 epigenetics  molecular docking  PRMT1  scaffold hopping  small-molecule inhibitor   Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文 FRONTIERS IN CHEMISTRY, 2017, 卷号: 5 作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia 收藏  |  浏览/下载：60/0  |  提交时间：2019/01/08 EGFR  tyrosine kinase inhibitors  anilinopyrtmidine  glycosides  carbohydrate-based drugs   PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文 CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266 作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Panax ginseng genome examination for ginsenoside biosynthesis 期刊论文 GigaScience, 2017, 卷号: 6, 期号: 11, 页码: 1-15 作者:  Xu, Jiang;  Chu, Yang;  Liao, Baosheng;  Xiao, Shuiming;  Yin, Qinggang 收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08 Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase 期刊论文 CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278 作者:  Dai, Xiaoyang;  Yan, Juan;  Fu, Xuhong;  Pan, Qiuming;  Sun, Danni 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611 作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Xie, Xiao-Yu;  Pan, You-Lu;  Li, Gang-Jian 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Pyridazine-3-carboxamides  CB2 agonist  Structure-activity relationships  Molecular docking  logP   Combined Virtual Screening and Substructure Search for Discovery of Novel FABP4 Inhibitors 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017, 卷号: 57, 期号: 9, 页码: 2329-2335 作者:  Cai, Haiyan;  Wang, Ting;  Yang, Zhuo;  Xu, Zhijian;  Wang, Guimin 收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 Computational Studies on Acetylcholinesterases 期刊论文 MOLECULES, 2017, 卷号: 22, 期号: 8 作者:  Xu, Yechun;  Cheng, Shanmei;  Sussman, Joel L.;  Silman, Israel;  Jiang, Hualiang 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 acetylcholinesterase  computational modeling and simulation  active-site gorge  ligand trafficking  oligomer  catalytic reaction mechanism