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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 W2476 ameliorates beta-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1024-1037 作者:  Li, Ting;  Lin, Guang-yao;  Zhong, Li;  Zhou, Yan;  Wang, Jia 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 diabetes  glucose  TXNIP  beta-cells  W2476  high-throughput screening   Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 5 作者:  Huang, Qi;  Wang, Ting;  Yang, Liu;  Wang, He-Yao 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 ginsenoside Rb2  NAFLD  type 2 diabetes  hepatosteatosis  autophagy  AMPK  sirt1   The metabolic ER stress sensor IRE1 alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity 期刊论文 NATURE IMMUNOLOGY, 2017, 卷号: 18, 期号: 5, 页码: 519-529 作者:  Shan, Bo;  Wang, Xiaoxia;  Wu, Ying;  Xu, Chi;  Xia, Zhixiong 收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 A small-molecule inhibitor of NF-kappa B-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury 期刊论文 FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 711-718 作者:  Ren, Xiaomeng;  Li, Xinzhi;  Jia, Linna;  Chen, Deheng;  Hou, Hai 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 NIK  liver injury  inflammation  CCl4   Ginsenoside Rb2 enhances the anti-inflammatory effect of omega-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 2, 页码: 192-200 作者:  Huang, Qi;  Wang, Ting;  Wang, He-yao 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 ginsenoside Rb2  LPS  alpha-linolenic acid  RAW264.7 cells  GPR120  inflammatory cytokines  iNOS  COX-2  IKK/NF-kappa B  MAPK pathway  diabetes  chronic inflammation   Downregulation of lipin-1 induces insulin resistance by increasing intracellular ceramide accumulation in C2C12 myotubes 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017, 卷号: 13, 期号: 1, 页码: 1-12 作者:  Huang, Shujuan;  Huang, Suling;  Wang, Xi;  Zhang, Qingli;  Liu, Jia 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 lipin-1  skeletal muscle  insulin resistance  lipid metabolism  ceramide   SH2B1 is Involved in the Accumulation of Amyloid-beta(42) in Alzheimer's Disease 期刊论文 JOURNAL OF ALZHEIMERS DISEASE, 2017, 卷号: 55, 期号: 2, 页码: 835-847 作者:  Shen, Yijun;  Xia, Yiling;  Meng, Shiquan;  Lim, Nastasia K. H.;  Wang, Wenan 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 Alzheimer's disease  amyloid-beta accumulation  diabetes  SH2B1 protein   W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway 期刊论文 Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1022 作者:  Ll Ting;  Lin Guangyao;  Zhong Li;  Zhou Yan;  Wang Jia 收藏  |  浏览/下载：5/0  |  提交时间：2020/12/24 diabetes  glucose  TXNIP  p-cells  W2476  high-throughput screening