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Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:  Yang, Xiuyan;  Zhang, Xi;  Huang, Min;  Song, Kun;  Li, Xuefen
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Functional role of the three conserved cysteines in the N domain of visual arrestin-1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 30, 页码: 12496-12502
作者:  Vishnivetskiy, Sergey A.;  Lee, Regina J.;  Zhou, X. Edward;  Franz, Andreas;  Xu, Qiuyi
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Zinc ion-induced conformational changes in new Delphi metallo-beta-lactamase 1 probed by molecular dynamics simulations and umbrella sampling 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 4, 页码: 3067-3075
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08


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