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科研机构
上海药物研究所 [20]
内容类型
期刊论文 [20]
发表日期
2017 [20]
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发表日期:2017
专题:上海药物研究所
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Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review
期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11
作者:
Shah, Sayed Asmat Ali
;
Akhter, Najeeb
;
Auckloo, Bibi Nazia
;
Khan, Ishrat
;
Lu, Yanbin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
cyanobacteria
secondary metabolites
biological properties and applications
A validated UPLC-MS/MS method coupled with protein precipitation and ion exchange solid phase extraction for the quantitation of porcine relaxin B29 in dog plasma and its application to a pharmacokinetic study
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2017, 卷号: 409, 期号: 28, 页码: 6559-6565
作者:
Su, Chong
;
Sun, Hui
;
Yang, Hong
;
Yin, Lei
;
Zhang, Jiwen
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Ion exchange solid phase extraction
LC-MS/MS
Porcine relaxin
Ultrahigh performance liquid chromatography
Defining the minimum substrate and charge recognition model of gamma-secretase
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 10, 页码: 1412-1424
作者:
Yan, Yan
;
Xu, Ting-Hai
;
Melcher, Karsten
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Alzheimer's disease
amyloid beta (A beta)
amyloid precursor protein (APP)
C99, gamma-secretase
minimum substrate
Notch protein
recognition model
Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the gamma - secretase cleavage sites
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 38, 页码: 15826-15837
作者:
Yan, Yan
;
Xu, Ting-Hai
;
Harikumar, Kaleeckal G.
;
Miller, Laurence J.
;
Melcher, Karsten
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides
期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 18, 页码: 4972-4975
作者:
Li, Zhihong
;
Huang, Rong
;
Xu, Hongtao
;
Chen, Jiakang
;
Zhan, Yuexiong
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Tryptic Peptides Bearing C-Terminal Dimethyllysine Need to Be Considered during the Analysis of Lysine Dimethylation in Proteomic Study
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2017, 卷号: 16, 期号: 9, 页码: 3460-3469
作者:
Chen, Ming
;
Zhang, Min
;
Zhai, Linhui
;
Hu, Hao
;
Liu, Ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
trypsin
lysine dimethylation
proteomics
terminal amine isotopic labeling of substrates (TAILS)
mass spectrometry analysis
Cyanobacterial peptides as a prototype for the design of cathepsin D inhibitors
期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 9, 页码: 701-706
作者:
Xu, Hao
;
Bao, Keting
;
Tang, Shuai
;
Ai, Jing
;
Hu, Haiyan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
cathepsin D
inhibitor
peptides
structural modification
transition-state mimics
Effective Conformational Sampling in Explicit Solvent with Gaussian Biased Accelerated Molecular Dynamics
期刊论文
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2017, 卷号: 13, 期号: 9, 页码: 4240-4252
作者:
Shao, Qiang
;
Zhu, Weiliang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/01/08
Asymmetric Synthesis of Chiral alpha-Substituted Mercaptoglycine Derivatives via alpha-Sulfenylation of Ni(II) Complex of Glycine and S-Substituted 4-Methylbenzenesulfonothioate
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 9, 页码: 1383-1390
作者:
Li, Jia
;
Song, Xiaohan
;
Zhou, Shengbin
;
Wang, Jiang
;
Liu, Hong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
alpha-sulfenylation
asymmetric synthesis
Ni(II) complex
chiral alpha-substituted mercaptoglycine derivatives
Aspartic Acid Side-Chain Benzyl Ester as a Multifunctionalization Precursor for Synthesis of Branched and Cyclic Arginylglycylaspartic Acid Peptides
期刊论文
SYNLETT, 2017, 卷号: 28, 期号: 15, 页码: 1966-1970
作者:
Tian, Xiaobo
;
Yu, Pengqiu
;
Tang, Yubo
;
Le, Zhiping
;
Huang, Wei
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
peptide side-chain ligation
side-chain benzyl ester
peptide hydrazide
arginylglycylaspartic acid peptides
branched cyclic peptides
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