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科研机构
上海药物研究所 [25]
内容类型
期刊论文 [25]
发表日期
2017 [25]
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发表日期:2017
专题:上海药物研究所
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Versatile Tailoring of NH2-Containing Metal-Organic Frameworks with Paddle-Wheel Units
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2017, 卷号: 23, 期号: 70, 页码: 17727-17733
作者:
Guo, Xiang-Guang
;
Zhang, Zai-Yong
;
Qiu, Sen
;
Su, Xiang
;
Wang, Ya-Bing
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
amines
luminescence
metal-organic frameworks
pillar structures
X-ray diffraction
Extending the Structural View of Class B GPCRs
期刊论文
TRENDS IN BIOCHEMICAL SCIENCES, 2017, 卷号: 42, 期号: 12, 页码: 946-960
作者:
de Graaf, Chris
;
Song, Gaojie
;
Cao, Can
;
Zhao, Qiang
;
Wang, Ming-Wei
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721
作者:
Li, Xiaokang
;
Wang, Huan
;
Xu, Yixiang
;
Liu, Wenwen
;
Gong, Qi
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
depression
multitarget-directed ligand
ChE inhibition
5-HT1A agonist
5-HT reuptake inhibition
Highly enantioselective Rh/chiral sulfur-olefin-catalyzed arylation of alkyl-substituted non-benzofused cyclic N-sulfonyl ketimines
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2017, 卷号: 4, 期号: 11, 页码: 2159-2162
作者:
Liu, Ming-Qing
;
Jiang, Tao
;
Chen, Wen-Wen
;
Xu, Ming-Hua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195
作者:
Hu, Jianping
;
Wang, Yingqing
;
Li, Yanlian
;
Xu, Lin
;
Cao, Danyan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
BRD4 inhibitor
Kinase
BI-2536
Dihydroquinoxalin-2(1H)-one
Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for fucose lectin identification and purification
期刊论文
CARBOHYDRATE RESEARCH, 2017, 卷号: 449, 页码: 143-152
作者:
Cai, Deqin
;
Xun, Chaochao
;
Tang, Feng
;
Tian, Xiaobo
;
Yang, Liyun
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/01/08
Core-fucose
Glycoconjugate
Glyco-dendrimer
Glyco-agarose
Fucose-specific lectin
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Recent approaches for asymmetric synthesis of alpha-amino acids via homologation of Ni(II) complexes
期刊论文
AMINO ACIDS, 2017, 卷号: 49, 期号: 9, 页码: 1487-1520
作者:
Wang, Yibing
;
Song, Xiaohan
;
Wang, Jiang
;
Moriwaki, Hiroki
;
Soloshonok, Vadim A.
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Asymmetric synthesis
alpha-Amino acids
Tailor-made amino acids
Ni(II) complexes
Practicality
Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 16, 页码: 7067-7083
作者:
Shi, Ying
;
Duan, Yan-Hui
;
Ji, Yue-Yang
;
Wang, Zhi-Long
;
Wu, Yan-Ran
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Incorporation of Dihydroartemisinin into Memantine Through a Propriate Spacer to Make Hybrid with Enhanced Effects to Protect PC12 Cells from Corticosterone-caused Impairments
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 4, 页码: 611-622
作者:
Zhang Lei
;
Zhou Fan
;
Zhang Laitao
;
Peng Lizhi
;
Guo Cuiping
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Artemisinin
Memantine
Neuroprotection
N-Methyl-D-aspartate(NMDA) receptor
Depression
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