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科研机构
西北高原生物研究所 [18]
上海药物研究所 [11]
水生生物研究所 [7]
北京大学 [5]
昆明植物研究所 [5]
高能物理研究所 [4]
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期刊论文 [75]
学位论文 [2]
会议论文 [1]
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2016 [78]
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Biochemist... [1]
Food Scien... [1]
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浏览/检索结果:
共78条,第1-10条
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发表日期:2016
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Polymorphism in a serine protease inhibitor gene and its association with the resistance of bay scallop (Argopecten irradians) to Listonella anguillarum challenge
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 59, 页码: 1-8
作者:
Siva, Vinu S.
;
Wang, Lingling
;
Qiu, Limei
;
Zhou, Zhi
;
Liu, Chao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2017/03/22
Argopecten irradians
Bay scallop
Single nucleotide polymorphism
Serine protease inhibitor
Disease resistance
Disease susceptibility
Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 981-991
作者:
Ma, Guang-Hui
;
Ye, Yan
;
Zhang, Dan
;
Xu, Xin
;
Si, Pei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
HFMD
EV71 3C(Pro)
Non-peptidyl inhibitor
Virtual screening
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells
期刊论文
Oncotarget, 2016, 卷号: 7, 期号: 47, 页码: 77096-77109
作者:
Qin, Dongjun
;
Wang, Weiwei
;
Lei, Hu
;
Luo, Hao
;
Cai, Haiyan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2017/02/14
CDDO-Me
ovarian cancer
USP7
CETSA
deubiquitinating enzymes
An Update on Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors: Opportunities and Challenges in Cancer Therapy
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 21, 页码: 9575-9598
作者:
Wang, Ying-Qing
;
Wang, Ping-Yuan
;
Wang, Yu-Ting
;
Yang, Guang-Fu
;
Zhang, Ao
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 382-393
作者:
Kondengaden, Shukkoor M.
;
Luo, Liu-fei
;
Huang, Kenneth
;
Zhu, Mengyuan
;
Zang, Lanlan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Lysine methyltransferase
G9a inhibitor
Leukemia
MALDI-TOF assay
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/05/09
Pyrotinib
Uplc/q-tof ms
Metabolism
Human
Cyp3a4
Drug-drug interaction
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Pyrotinib
UPLC/Q-TOF MS
Metabolism
Human
CYP3A4
Drug-drug interaction
Rational Design of a Profluorescent Substrate for S-adenosylhomocysteine Hydrolase and its Applications in Bioimaging and Inhibitor Screening
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2016, 卷号: 8, 期号: 39, 页码: 25818-25824
作者:
Zhao, Guangjiu
;
Zheng, Daoyuan
;
Li, Dongmei
;
Wang, Jiayue
;
Wang, Yanni
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/06/20
S-adenosylhomocysteine Hydrolase
Fluorogenic Substrate
Kinetic Study
Bioimaging Inhibitor Screening
Aptamer and PNIPAAm co-conjugated nanoparticles regulate activity of enzyme with different temperature
期刊论文
TALANTA, 2016, 卷号: 159, 页码: 47-54
作者:
Yu, Jiemiao
;
Yang, Liangrong
;
Liang, Xiangfeng
;
Dong, Tingting
;
Qu, Hongnan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2016/11/14
Temperature responsive
Gold nanoparticles
Aptamer
Thrombin
Regulation
Activity
Aptamer and PNIPAAm co-conjugated nanoparticles regulate activity of enzyme with different temperature
期刊论文
TALANTA, 2016, 卷号: 159, 期号: OCT, 页码: 47-54
作者:
Yu, Jiemiao
;
Yang, Liangrong
;
Liang, Xiangfeng
;
Dong, Tingting
;
Qu, Hongnan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2016/11/21
Temperature responsive
Gold nanoparticles
Aptamer
Thrombin
Regulation
Activity
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