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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2016     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 981-991 作者:  Ma, Guang-Hui;  Ye, Yan;  Zhang, Dan;  Xu, Xin;  Si, Pei 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 HFMD  EV71 3C(Pro)  Non-peptidyl inhibitor  Virtual screening   Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 382-393 作者:  Kondengaden, Shukkoor M.;  Luo, Liu-fei;  Huang, Kenneth;  Zhu, Mengyuan;  Zang, Lanlan 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 Lysine methyltransferase  G9a inhibitor  Leukemia  MALDI-TOF assay   Rational Design of a Profluorescent Substrate for S-adenosylhomocysteine Hydrolase and its Applications in Bioimaging and Inhibitor Screening 期刊论文 ACS APPLIED MATERIALS & INTERFACES, 2016, 卷号: 8, 期号: 39, 页码: 25818-25824 作者:  Zhao, Guangjiu;  Zheng, Daoyuan;  Li, Dongmei;  Wang, Jiayue;  Wang, Yanni 收藏  |  浏览/下载：18/0  |  提交时间：2019/06/20 S-adenosylhomocysteine Hydrolase  Fluorogenic Substrate  Kinetic Study  Bioimaging Inhibitor Screening   Nmr-based platform for fragment-based lead discovery used in screening brd4-targeted compounds 期刊论文 Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 7, 页码: 984-993 作者:  Yu, Jun-lan;  Chen, Tian-tian;  Zhou, Chen;  Lian, Fu-lin;  Tang, Xu-long 收藏  |  浏览/下载：23/0  |  提交时间：2019/05/09 Fragment-based lead discovery  Nmr  Bromodomain  Brd4 inhibitors   NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 984-993 作者:  Yu, Jun-lan;  Chen, Tian-tian;  Zhou, Chen;  Lian, Fu-lin;  Tang, Xu-long 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 fragment-based lead discovery  NMR  bromodomain  BRD4 inhibitors   Discovery of new cellulases from the metagenome by a metagenomics-guided strategy 期刊论文 BIOTECHNOLOGY FOR BIOFUELS, 2016 Yang, Chao; Xia, Yu; Qu, Hong; Li, An-Dong; Liu, Ruihua; Wang, Yubo; Zhang, Tong 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/04 Cellulase  Glycoside hydrolase  Metagenome  BACILLUS-SUBTILIS  IDENTIFICATION  RESOURCES  BACTERIA  BIOMASS  SYSTEM  VELVET  GENES  TAT   DNA Polymerase kappa Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus 期刊论文 PLOS PATHOGENS, 2016 Qi, Yonghe; Gao, Zhenchao; Xu, Guangwei; Peng, Bo; Liu, Chenxuan; Yan, Huan; Yao, Qiyan; Sun, Guoliang; Liu, Yang; Tang, Dingbin; Song, Zilin; He, Wenhui; Sun, Yinyan; Guo, Ju-Tao; Li, Wenhui 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03 NUCLEOTIDE-EXCISION-REPAIR  PLUS-STRAND DNA  VIRAL-DNA  IN-VITRO  HEPATOCYTE CULTURES  TUPAIA HEPATOCYTES  ENVELOPE PROTEINS  HBV REPLICATION  POL-KAPPA  INFECTION   Discovery of Non-ATP-Competitive Inhibitors of Polo-like Kinase1 期刊论文 CHEMMEDCHEM, 2016 Yun, Taikangxiang; Qin, Tan; Liu, Ying; Lai, Luhua 收藏  |  浏览/下载：3/0  |  提交时间：2017/12/03 inhibitors  kinase domain  non-ATP binding site  polo-like kinase1  virtual screening  1 PLK1 INHIBITORS  P38 MAP KINASE  CANCER-THERAPY  BINDING-SITE  BOX DOMAIN  PROTEIN  POLO-LIKE-KINASE-1  IDENTIFICATION  APOPTOSIS  DESIGN   MST与水环境生物源污染定量化溯源 期刊论文 农业环境科学学报, 2016, 卷号: 35, 期号: 2, 页码: 205-211 作者:  郭萍;  李红娜;  李峰 收藏  |  浏览/下载：14/0  |  提交时间：2016/12/06 微生物溯源技术  生物源污染  定量化溯源