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上海药物研究所 [39]
北京大学 [19]
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期刊论文 [167]
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2016 [169]
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Zebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7
期刊论文
JOURNAL OF IMMUNOLOGY, 2016, 卷号: 197, 期号: 12, 页码: 4736-4749
作者:
Liu, Xing
;
Cai, Xiaolian
;
Zhang, Dawei
;
Xu, Chenxi
;
Xiao, Wuhan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/09/05
Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway
期刊论文
PHYTOMEDICINE, 2016, 卷号: 23, 期号: 14, 页码: 1806-1813
作者:
Zhang, Liu
;
Zhang, Hui
;
Li, Xueyan
;
Jia, Bingjie
;
Yang, Yuyu
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  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Miltirone
Nrf2
HO-1
Endothelial dysfunction
Oxidative stress
The P Protein of Spring Viremia of Carp Virus Negatively Regulates the Fish Interferon Response by Inhibiting the Kinase Activity of TANK-Binding Kinase 1
期刊论文
JOURNAL OF VIROLOGY, 2016, 卷号: 90, 期号: 23, 页码: 10728-10737
作者:
Li, Shun
;
Lu, Long-Feng
;
Wang, Zhao-Xi
;
Lu, Xiao-Bing
;
Chen, Dan-Dan
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  |  
浏览/下载:31/0
  |  
提交时间:2019/09/05
Deficiency of dietary niacin decreases digestion and absorption capacities via declining the digestive and brush border enzyme activities and downregulating those enzyme gene transcription related to TOR pathway of the hepatopancreas and intestine in young grass carp (Ctenopharyngodon idella)
期刊论文
AQUACULTURE NUTRITION, 2016, 卷号: 22, 期号: 6, 页码: 1267-1282
作者:
Li, S. -Q.
;
Feng, L.
;
Jiang, W. -D.
;
Liu, Y.
;
Wu, P.
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  |  
浏览/下载:223/0
  |  
提交时间:2019/09/05
Ctenopharyngodon idella
enzyme activity
gene expression
growth
niacin
TOR signalling pathway
A CgIFNLP receptor from Crassostrea gigas and its activation of the related genes in human JAK/STAT signaling pathway
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2016, 卷号: 65, 页码: 98-106
作者:
Zhang, Ran
;
Liu, Rui
;
Xin, Lusheng
;
Chen, Hao
;
Li, Chenghua
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  |  
浏览/下载:33/0
  |  
提交时间:2016/12/05
Crassostrea gigas
Interferon
Interferon receptor
Poly (I: C)
Interferon stimulated genes
A cgifnlp receptor from crassostrea gigas and its activation of the related genes in human jak/stat signaling pathway
期刊论文
Developmental and comparative immunology, 2016, 卷号: 65, 页码: 98-106
作者:
Zhang, Ran
;
Liu, Rui
;
Xin, Lusheng
;
Chen, Hao
;
Li, Chenghua
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  |  
浏览/下载:50/0
  |  
提交时间:2019/05/09
Crassostrea gigas
Interferon
Interferon receptor
Poly (i: c)
Interferon stimulated genes
Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl) benzamides as novel RET kinase inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 23, 页码: 5679-5684
作者:
Han, Mei
;
Li, Shan
;
Ai, Jing
;
Sheng, Rong
;
Hu, Yongzhou
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  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
RET kinase inhibitor
1,2,4-Oxadiazole
Anti-cancer therapy
pVHL mediates K63-linked ubiquitination of IKK beta, leading to IKK beta inactivation
期刊论文
CANCER LETTERS, 2016, 卷号: 383, 期号: 1, 页码: 1-8
作者:
Wang, Yuxin
;
Zhao, Wenting
;
Gao, Qiang
;
Fan, Li
;
Qin, Yanqing
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  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
IKK beta
pVHL
Ubiquitination
Staurosporine as an agonist for induction of GLUT4 translocation, identified by a pH-sensitive fluorescent IRAP-mOrange2 probe
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 480, 期号: 4, 页码: 534-538
作者:
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  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Diabetes
pH-sensitive fluorescent probe
GLUT4 translocation
Staurosporine
Insulin additive analogue
Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 22, 页码: 5399-5402
作者:
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  |  
浏览/下载:66/0
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提交时间:2019/01/08
EML4-ALK kinase
Oxidative metabolism
Benzo[b]carbazolone
hERG
Antitumor activity
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