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Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 23, 页码: 6206-6214
作者:  Zhang, Jiankang;  Gao, Lixin;  Xi, Jianjun;  Sheng, Li;  Zhao, Yanmei
收藏  |  浏览/下载:51/0  |  提交时间:2019/01/08
The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog 期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7
作者:  Jin, Jiali;  Liu, Jian;  Chen, Cong;  Liu, Zhenping;  Jiang, Cong
收藏  |  浏览/下载:95/0  |  提交时间:2019/01/08
Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 38, 页码: 20125-20135
作者:  Ding, Guangjin;  Chen, Peilin;  Zhang, Hui;  Huang, Xiaojie;  Zang, Yi
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer 期刊论文
CANCER CELL, 2016, 卷号: 30, 期号: 3, 页码: 474-484
作者:  Guo, Zhong-Qiang;  Zheng, Tong;  Chen, Baoen;  Luo, Cheng;  Ouyang, Sisheng
收藏  |  浏览/下载:37/0  |  提交时间:2019/01/08
Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells 期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 7
作者:  Yue, Qingxi;  Zhen, Hong;  Huang, Ming;  Zheng, Xi;  Feng, Lixing
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting beta 1 subunit expression and disrupting proteasome assembly 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 908-918
作者:  Sun, Peng;  Feng, Li-xing;  Zhang, Dong-mei;  Liu, Miao;  Liu, Wang
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Y-632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo 期刊论文
CANCER SCIENCE, 2016, 卷号: 107, 期号: 6, 页码: 782-790
作者:  Wang, Wenqian;  Liu, Yang;  Zhao, Zhixin;  Xie, Chengying;  Xu, Yongping
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
X66, a novel N-terminal heat shock protein 90 inhibitor, exerts antitumor effects without induction of heat shock response 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 20, 页码: 29648-29663
作者:  Zhao, Zhixin;  Zhu, Jianming;  Quan, Haitian;  Wang, Guimin;  Li, Bo
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome 期刊论文
SCIENCE, 2016, 卷号: 351, 期号: 6275
作者:  Shi, Yuan;  Chen, Xiang;  Elsasser, Suzanne;  Stocks, Bradley B.;  Tian, Geng
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
bufalinderivativebf211inhibitsproteasomeactivityinhumanlungcancercellsinvitrobyinhibiting1subunitexpressionanddisruptingproteasomeassembly 期刊论文
actapharmacologicasinica, 2016, 卷号: 000, 期号: 007, 页码: 908
作者:  Pengsun;  Feng Lixing;  Zhang Dongmei;  Liu Miao;  Liu Wang
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/01


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