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浏览/检索结果: 共18条，第1-10条 帮助 限定条件 发表日期：2014    专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Engineered TAL Effector modulators for the large-scale gain-of-function screening 期刊论文 核酸研究, 2014 Zhang, Hanshuo; Li, Juan; Hou, Sha; Wang, Gancheng; Jiang, Mingjun; Sun, Changhong; Hu, Xiongbing; Zhuang, Fengfeng; Dai, Zhifei; Dai, Junbiao; Xi, Jianzhong Jeff 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/13 TRANSCRIPTION FACTORS  GENOME BROWSER  III EFFECTORS  MOUSE MODEL  EXPRESSION  PROTEINS  UCSC   An allosteric model of the inositol trisphosphate receptor with nonequilibrium binding 其他 2014-01-01 Jia, Chen; Jiang, Daquan; Qian, Minping 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/10 adaptation  overshoot  nonequilibrium  Monod-Wyman-Changeux model  Xenopus oocyte  patch-clamp  SINGLE-CHANNEL KINETICS  CA2+ RELEASE CHANNELS  1,4,5-TRISPHOSPHATE RECEPTOR  IP3 RECEPTORS  PARTIAL INACTIVATION  RAPID ACTIVATION  STEADY-STATE  CALCIUM  ADAPTATION  PHOSPHORYLATION   Protein-Protein Interface Analysis and Hot Spots Identification for Chemical Ligand Design 期刊论文 current pharmaceutical design, 2014 Chen, Jing; Ma, Xiaomin; Yuan, Yaxia; Pei, Jianfeng; Lai, Luhua 收藏  |  浏览/下载：7/0  |  提交时间：2015/11/13 Protein-protein interface analysis  small molecular binder  binding site detection  ligandability  hot spots  Pocket V.3  SMALL-MOLECULE INHIBITORS  DRUG DISCOVERY  BINDING-SITES  CONFORMATIONAL DYNAMICS  STRUCTURAL BIOLOGY  TRANSIENT POCKETS  PREDICTION  ALLOSTERY  DRUGGABILITY  MODULATION   Discovery of Novel Allosteric Effectors Based on the Predicted Allosteric Sites for Escherichia coli D-3-Phosphoglycerate Dehydrogenase 期刊论文 plos one, 2014 Wang, Qian; Qi, Yifei; Yin, Ning; Lai, Luhua 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/13 SERINE BIOSYNTHESIS  3-PHOSPHOGLYCERATE DEHYDROGENASE  PHOSPHOGLYCERATE DEHYDROGENASE  MYCOBACTERIUM-TUBERCULOSIS  HYBRID TETRAMERS  BINDING  MODEL  METABOLISM  MECHANISM  PATHWAYS   Denaturant effect on free energy of protein unfolding process 其他 2014-01-01 李茂东; 刘志荣 收藏  |  浏览/下载：3/0  |  提交时间：2015/10/23 Protein denaturation transfer model binding model   变性剂对蛋白质解折叠过程自由能的影响 其他 2014-01-01 李茂东; 刘志荣 收藏  |  浏览/下载：2/0  |  提交时间：2015/10/24 蛋白质变性  模型对比  Transfer model  Binding model   Long-chain flavodoxin FldB from Escherichia coli 期刊论文 生物分子核磁共振杂志, 2014 Ye, Qian; Fu, Wenyu; Hu, Yunfei; Jin, Changwen 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/10 MODEL-FREE APPROACH  MAGNETIC-RESONANCE RELAXATION  BACKBONE DYNAMICS  DIFFERENTIATING LOOP  OXIDIZED FLAVODOXIN  VULGARIS FLAVODOXIN  N-15 RELAXATION  FMN-BINDING  DOMAIN  MACROMOLECULES   Inhibition and Mechanism of HDAC8 Revisited 期刊论文 journal of the american chemical society, 2014 Chen, Kai; Zhang, Xiaoxiao; Wu, Yun-Dong; Wiest, Olaf 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 HISTONE DEACETYLASE INHIBITORS  AB-INITIO QM/MM  ZINC-BINDING GROUPS  ACTIVE-SITE  CATALYTIC-ACTIVITY  CRYSTAL-STRUCTURE  HYDROXAMIC ACIDS  CANCER-THERAPY  PROTEIN  TSA   Effects of charging on the chromophores of dissolved organic matter from the Rio Negro basin 期刊论文 水研究, 2014 Yan, Mingquan; Korshin, Gregory V.; Claret, Francis; Croue, Jean-Philippe; Fabbricino, Massimiliano; Gallard, Herve; Schaefer, Thorsten; Benedetti, Marc F. 收藏  |  浏览/下载：22/0  |  提交时间：2015/11/11 Amazon river  Absorbance  Deprotonation  Dissolved organic matter  NEXAFS  NICA-Donnan model  AQUATIC HUMIC SUBSTANCES  NICA-DONNAN MODEL  AMAZON-RIVER  OPTICAL-PROPERTIES  FULVIC-ACIDS  FLUORESCENCE SPECTROSCOPY  MASS-SPECTROMETRY  PROTON-BINDING  SURFACE WATERS  MOLECULAR-SIZE   Myosin Light Chain Kinase (MLCK) Regulates Cell Migration in a Myosin Regulatory Light Chain Phosphorylation-independent Mechanism 期刊论文 journal of biological chemistry, 2014 Chen, Chen; Tao, Tao; Wen, Cheng; He, Wei-Qi; Qiao, Yan-Ning; Gao, Yun-Qian; Chen, Xin; Wang, Pei; Chen, Cai-Ping; Zhao, Wei; Chen, Hua-Qun; Ye, An-Pei; Peng, Ya-Jing; Zhu, Min-Sheng 收藏  |  浏览/下载：16/0  |  提交时间：2015/11/13 SMOOTH-MUSCLE CONTRACTION  MEMBRANE TENSION  RHO-KINASE  EXTRACELLULAR-MATRIX  ADHESION DYNAMICS  ACTIN CONNECTION  CA2+ SENSITIVITY  DISTINCT ROLES  IN-VIVO  MOTILITY