Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes

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	Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes
	Shi GuoHua 1; Fu LingLing 2; Li XiQi 1; Jiang ChunHui 3; Zhang YuDong 1
刊名	SCIENCE CHINA-LIFE SCIENCES
	2014-12-01
卷号	57 期号:12 页码:1213-1217
关键词	ophthalmology glaucomatous Schlemm's canal morphometry
英文摘要	A custom built 1310 nm center wavelength swept source optical coherence tomography instrument was used to measure morphological changes in treated and newly diagnosed untreated glaucomatous human Schlemm's canal (SC). Thirty-seven primary open-angle glaucoma patients were divided into two groups depending on the patients having been treated or not. The statistical results showed that there were significant differences between the treated and untreated groups' SC areas (treated, 7935.6875 +/- 680.003 mu m(2); untreated, 3890.71875 +/- 871.49844 mu m(2); P < 0.001), the circumferences (treated, 580.37891 +/- 44.96529 mu m; untreated, 381.9026 +/- 41.22123 mu m; P < 0.001), and the long diameters (treated, 272.87806 +/- 25.7254 mu m; untreated, 185.24047 +/- 19.72786 mu m; P < 0.001). We hypothesize that, after drug treatment, the SC will expand and the morphometric values especially the areas will become larger, thus helping to reduce intraocular pressure.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biology
研究领域[WOS]	Life Sciences & Biomedicine - Other Topics
关键词[WOS]	OPEN-ANGLE GLAUCOMA ; CIRCADIAN IOP ; PRESSURE
收录类别	SCI
语种	英语
WOS记录号	WOS:000346187000009
公开日期	2015-12-24
内容类型	期刊论文
源URL	[http://ir.ioe.ac.cn/handle/181551/2506]
专题	光电技术研究所_光电技术研究所被WoS收录文章
作者单位	1.Chinese Acad Sci, Inst Opt & Elect, Key Lab Adapt Opt, Chengdu 610209, Peoples R China 2.Karamay Cent Hosp, Karamay 834000, Peoples R China 3.Fudan Univ, Dept Ophthalmol & Vis Sci Eye & ENT, Shanghai 200031, Peoples R China
推荐引用方式 GB/T 7714	Shi GuoHua,Fu LingLing,Li XiQi,et al. Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes[J]. SCIENCE CHINA-LIFE SCIENCES,2014,57(12):1213-1217.
APA	Shi GuoHua,Fu LingLing,Li XiQi,Jiang ChunHui,&Zhang YuDong.(2014).Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes.SCIENCE CHINA-LIFE SCIENCES,57(12),1213-1217.
MLA	Shi GuoHua,et al."Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes".SCIENCE CHINA-LIFE SCIENCES 57.12(2014):1213-1217.