Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template | |
Li, Senwu1,2; Yang, Kaiguang1; Liu, Jianxi1,2; Jiang, Bo1; Zhang, Lihua1; Zhang, Yukui1 | |
刊名 | analytical chemistry |
2015-05-05 | |
卷号 | 87期号:9页码:4617-4620 |
通讯作者 | 张丽华 |
英文摘要 | the specific recognition of biomolecules by artificial antibodies has inspired fascination among chemists and biologists. herein, we propose a new method to prepare epitope-oriented surface-imprinted nanoparticles with high template utilization efficiency. using a his-tag as the anchor to facilitate the epitope immobilization/removal and the self-polymerization of dopamine to control the imprinted shell thickness, the prepared epitope-imprinted nanoparticles show specific recognition of the target protein. moreover, with improved hydrophilicity of the his-tag-anchored epitope, this method opens up a universal route for imprinting epitopes with various polarities. |
学科主题 | 物理化学 |
WOS标题词 | science & technology ; physical sciences |
类目[WOS] | chemistry, analytical |
研究领域[WOS] | chemistry |
关键词[WOS] | silica nanoparticles ; protein recognition ; polymers ; polymerization ; extraction ; separation ; cavities |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000354153600007 |
公开日期 | 2015-11-17 |
内容类型 | 期刊论文 |
源URL | [http://159.226.238.44/handle/321008/143715] |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Senwu,Yang, Kaiguang,Liu, Jianxi,et al. Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template[J]. analytical chemistry,2015,87(9):4617-4620. |
APA | Li, Senwu,Yang, Kaiguang,Liu, Jianxi,Jiang, Bo,Zhang, Lihua,&Zhang, Yukui.(2015).Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template.analytical chemistry,87(9),4617-4620. |
MLA | Li, Senwu,et al."Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template".analytical chemistry 87.9(2015):4617-4620. |
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