Pt-Sn/?-Al2O3-Catalyzed Highly Efficient Direct Synthesis of Secondary and Tertiary Amines and Imines

	Pt-Sn/?-Al2O3-Catalyzed Highly Efficient Direct Synthesis of Secondary and Tertiary Amines and Imines
	He, Wei 1; Wang, Liandi 1; Sun, Chenglin 1; Wu, Kaikai 1; He, Songbo 1; Chen, Jiping 1; Wu, Ping 1; Yu, Zhengkun 1,2
刊名	chemistry-a european journal
	2011-11-01
卷号	17 期号:47 页码:13308-13317
关键词	alcohols alkylation amines borrowing hydrogen imines
英文摘要	versatile syntheses of secondary and tertiary amines by highly efficient direct n-alkylation of primary and secondary amines with alcohols or by deaminative self-coupling of primary amines have been successfully realized by means of a heterogeneous bimetallic ptsn/?-al2o3 catalyst (0.5 wt?% pt, pt/sn molar ratio=1:3) through a borrowing-hydrogen strategy. in the presence of oxygen, imines were also efficiently prepared from the tandem reactions of amines with alcohols or between two primary amines. the proposed mechanism reveals that an alcohol or amine substrate is initially dehydrogenated to an aldehyde/ketone or nh-imine with concomitant formation of a [ptsn] hydride. condensation of the aldehyde/ketone species or deamination of the nh-imine intermediate with another molecule of amine forms an n-substituted imine which is then reduced to a new amine product by the in-situ generated [ptsn] hydride under a nitrogen atmosphere or remains unchanged as the final product under an oxygen atmosphere. the ptsn/?-al2o3 catalyst can be easily recycled without pt metal leaching and has exhibited very high catalytic activity toward a wide range of amine and alcohol substrates, which suggests potential for application in the direct production of secondary and tertiary amines and n-substituted imines.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	catalyzed n-alkylation ; borrowing hydrogen methodology ; supported ruthenium hydroxide ; direct amide synthesis ; selective synthesis ; aliphatic-amines ; direct amination ; tandem synthesis ; aromatic-amines ; gamma-alumina
收录类别	SCI ; CCR
语种	英语
WOS记录号	WOS:000298058500027
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/142507]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
推荐引用方式 GB/T 7714	He, Wei,Wang, Liandi,Sun, Chenglin,et al. Pt-Sn/?-Al2O3-Catalyzed Highly Efficient Direct Synthesis of Secondary and Tertiary Amines and Imines[J]. chemistry-a european journal,2011,17(47):13308-13317.
APA	He, Wei.,Wang, Liandi.,Sun, Chenglin.,Wu, Kaikai.,He, Songbo.,...&Yu, Zhengkun.(2011).Pt-Sn/?-Al2O3-Catalyzed Highly Efficient Direct Synthesis of Secondary and Tertiary Amines and Imines.chemistry-a european journal,17(47),13308-13317.
MLA	He, Wei,et al."Pt-Sn/?-Al2O3-Catalyzed Highly Efficient Direct Synthesis of Secondary and Tertiary Amines and Imines".chemistry-a european journal 17.47(2011):13308-13317.