Readily available sulfamide-amine alcohols for enantioselective phenylacetylene addition to aldehydes in the absence of Ti(O(i)Pre)(4)

	Readily available sulfamide-amine alcohols for enantioselective phenylacetylene addition to aldehydes in the absence of Ti(O(i)Pre)(4)
	Mao, JC; Wan, BS; Wu, F; Lu, SW
刊名	chirality
	2005-05-15
卷号	17 期号:5 页码:245-249
英文摘要	ephedrine-derived sulfamide-amine alcohol 3 was found to be an effective catalyst for the asymmetric phenylacetylene addition to aldehydes at room temperature without using ti((opr)-pr-i)(4) and zn(otf)(2.) it afforded the propargylic alcohols in high yields (up to 99%) and good enantioselectivities (up to 84% ee), which were much higher than that based on n-methylephedrine under the same reaction conditions. its weakly coordinative sulfonamide moiety of the ligand plays an important role for further acceleration and stereocontrol in the alkynylation. (c) 2005 wiley-liss, inc.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	chemistry, medicinal ; chemistry, analytical ; chemistry, organic ; pharmacology & pharmacy
研究领域[WOS]	pharmacology & pharmacy ; chemistry
关键词[WOS]	aromatic-aldehydes ; propargylic alcohols ; alkyne additions ; ligand ; alkynylation ; binol ; dialkylzincs
收录类别	SCI
语种	英语
WOS记录号	WOS:000228825400002
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/139786]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Grad Sch, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Mao, JC,Wan, BS,Wu, F,et al. Readily available sulfamide-amine alcohols for enantioselective phenylacetylene addition to aldehydes in the absence of Ti(O(i)Pre)(4)[J]. chirality,2005,17(5):245-249.
APA	Mao, JC,Wan, BS,Wu, F,&Lu, SW.(2005).Readily available sulfamide-amine alcohols for enantioselective phenylacetylene addition to aldehydes in the absence of Ti(O(i)Pre)(4).chirality,17(5),245-249.
MLA	Mao, JC,et al."Readily available sulfamide-amine alcohols for enantioselective phenylacetylene addition to aldehydes in the absence of Ti(O(i)Pre)(4)".chirality 17.5(2005):245-249.