Synthesis, characterization and evaluation of a novel ester-bonded for reversed-phase HPLC

	Synthesis, characterization and evaluation of a novel ester-bonded for reversed-phase HPLC
	Huang, XJ; Liu, XL; Wang, JD; Cong, RZ
刊名	chemical journal of chinese universities-chinese
	2002-09-01
卷号	23 期号:9 页码:1684-1687
关键词	silane coupling agent high performance liquid chromatography reversed phase packing ester-bonded stationary phase
英文摘要	a novel ester-bonded packing for reversed-phase hplc(rp-hplc) was synthesized by reacting octanoic acid with beta-(3, 4-epoxycyclohexyl) ethyltrimethoxy silane and then the intermediate product was coupled onto porous silica. characterization of the prepared packing was carried out with elemental analysis, solid-state c-13 nmr, and fourier transform infrared spectrometry. hydrophobicity, selectivity and silanophilic activity of the packing were evaluated by using organic components including acidic, basic and neutral analytes as probe molecules and methanol-water as binary mobile phase. the usage ranges of ph and stability of the packing were also evaluated. the results show that, the novel stationary phase has excellent. chromatographic properties and resist to hydrolysis between ph = 2. 5-7. 5, it can be used for the separation of basic solutes efficiently.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
收录类别	SCI
语种	英语
WOS记录号	WOS:000178056800013
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/139186]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China
推荐引用方式 GB/T 7714	Huang, XJ,Liu, XL,Wang, JD,et al. Synthesis, characterization and evaluation of a novel ester-bonded for reversed-phase HPLC[J]. chemical journal of chinese universities-chinese,2002,23(9):1684-1687.
APA	Huang, XJ,Liu, XL,Wang, JD,&Cong, RZ.(2002).Synthesis, characterization and evaluation of a novel ester-bonded for reversed-phase HPLC.chemical journal of chinese universities-chinese,23(9),1684-1687.
MLA	Huang, XJ,et al."Synthesis, characterization and evaluation of a novel ester-bonded for reversed-phase HPLC".chemical journal of chinese universities-chinese 23.9(2002):1684-1687.